The best drugs for biorevitalization – how to choose?

Update date: 02/11/2021 12:53:58 40275 Share:

Author of the article: Demidova Anna Viktorovna

*Review of the best according to the editors of simplerule.ru. About the selection criteria. This material is subjective in nature, does not constitute advertising and does not serve as a purchase guide. Before purchasing, consultation with a specialist is required.

Biorevitalization is a procedure that involves the introduction of drugs with hyaluronic acid (HA) into or under the skin. Hyaluronic acid is one of the main components of the extracellular matrix and is present in many tissues. It has a special structure and a large molecular weight of the molecule, therefore it is able to hold a significant amount of water. This is of great importance in cosmetology.

Products used during biorevitalization may contain only hyaluronic acid or HA, supplemented with vitamins, minerals, and plant extracts. After this cosmetic procedure, the tone of the face is evened out, the skin becomes smooth, elastic and smoothed out from shallow wrinkles. The main areas for such manipulation are the face, décolleté, and hands.

When is biorevitalization needed?

Some resort to biorevitalization for the purpose of prevention. But this procedure is especially appropriate in such cases:

1. The skin becomes dry, dehydrated, and loses elasticity and density.
2. Due to insufficient hydration, shallow wrinkles appear.
3. The skin was subjected to traumatic effects: laser rejuvenation, medium chemical peeling, surgery.
4. Increased activity of the glands that produce sebum, leading to enlarged pores, oily shine and other problems.
5. Dull complexion, hyperpigmentation, decreased turgor due to frequent exposure to stress, smoking, and excess ultraviolet radiation.

Typically, people aged 30 years and older resort to biorevitalization. But it is appropriate to carry it out once at the age of 20, if the skin has been exposed to excessive exposure to sea water and ultraviolet radiation.

Correct selection of the drug

Biorevitalizants may contain different components, but hyaluronic acid must be present among them. Its stabilized and unstabilized forms can be used. The second provides maximum hydration, which is why it is most often used for biorevitalization.

For younger dermis (up to 30 years), biorevitalizants containing concentrated HA that has not been purified are ideal. Such preparations are optimal for thin and dry skin. They will be a godsend for epidermis prone to hyperpigmentation or early appearance of wrinkles.

For more mature skin, it is advisable to use combination preparations containing not only hyaluronic acid, but also other useful components. Such complexes have an excellent effect on the skin, allowing you to solve all major cosmetic problems in a few procedures.

When choosing a drug to be used during biorevitalization, the following concepts should be taken into account:

1. The age of the person. Some drugs have a slight lifting effect, while others are more suitable for skin with noticeable geriatric changes.
2. Manufacturer. There are brands that have been producing very high-quality products for years. They should be given priority first.
3. Dosage. It is better to choose drugs that are already packaged in separate syringes. This makes it difficult to make a mistake with the dosage.
4. Syringe volume. If the biorevitalization procedure is planned only for the face, then it is enough to take 1 ml. If, in addition to the face, the neck, décolleté and hands will be treated, then it is advisable to take 3 ml of the drug.
5. Duration of effect. Different manufacturers indicate different periods - 2-3 months or a whole year.

Contraindications should also be taken into account, since not all people can be injected with such drugs. In our review we will look at the best biorevitalizants from manufacturers from various countries.

How does hyaluronic acid work?

Everyone knows about the importance of such a substance as hyaluronic acid for the skin. This substance is a polysaccharide that takes part in the most important cellular processes. With age, its synthesis in the body weakens due to aging and due to the influence of external factors. Creams with hyaluronic acid are widely available on the market. Every cosmetic brand has such a line in its assortment. But the nuance is that the hyaluronic acid molecule is quite large to pass through the skin and moisturize it. This is a marketing ploy, and not at all harmless. When air humidity drops to 40%, hyaluronic acid draws moisture from the skin into the external environment to establish balance. As a result, instead of hydration, you can get cell dehydration.

Biorevitalization of the face with hyaluronic acid is a more effective method of saturating the skin with this polysaccharide. Synthesized hyaluronate polymer is used for the procedure. The artificially obtained substance is permanently fixed in the epidermis and does not break down into its components.

Cosmetologists claim that too much hyaluronic acid is harmful to the skin. The optimal percentage of the substance in biorevitalizant is no more than 1%.

Maintaining youth occurs by stimulating the production of collagen and elastin fibers in the epidermis. Biorevitalization works well on both mature and young skin. To enhance the rejuvenation effect, after a course of procedures you can do chemical or laser peeling.

Rating of the best drugs for biorevitalization

The best drugs for biorevitalization from Europe

Cosmetologists performing the biorevitalization procedure widely use preparations from Italy, Switzerland, and Russia in their practice. Each specialist has his own preferences, but when selecting a specific drug, they take into account the age category of the clients, as well as the changes that have befallen their skin.

Jalupro

Rating: 4.9

The drug Jalupro is produced by the Italian laboratory Professional Dietetics. Its main component is unstabilized hyaluronic acid. This drug also contains a set of amino acids. This composition ensures safe and effective biorevitalization, after which clinical results quickly occur.

Each package of Jalupro contains 2 bottles of amino acids and 2 ampoules (1.5 ml) of 1% HA. Immediately before biorevitalization, the cosmetologist mixes these components. One package is enough for two procedures. In total you need to conduct 3-4 sessions. Manipulations are carried out once every 2 weeks. On the recommendation of a doctor, maintenance procedures can also be performed 1-2 times every 30-60 days.

Even after the first manipulation, the face is noticeably transformed. The skin looks fresher and more elastic. After the second biorevitalization, she looks very hydrated and radiant. In this case, there is even no need to use creams. After three procedures, the skin is cleared of post-acne marks. However, the first manipulation may be somewhat painful. After it, hematomas (disappear in 5-7 days) and papules (disappear in 2-3 days) often remain.

Advantages

1. multi-component, effective composition;
2. one package is enough for 2 sessions;
3. makes the skin more elastic and fresh;
4. eliminates peeling, moisturizes;
5. eliminates acne marks.

Flaws

1. Doesn't work on deep wrinkles.

IAL-system

Rating: 4.8

The Italian brand Fidia Farmaceutici produces the drug IAL-system. Its effectiveness is explained by the presence of native unmodified hyaluronic acid in the composition. Its molecules were not subjected to artificial stabilization. They are devoid of chemical bonds with each other, therefore, after administration, they are immediately included in the metabolism in the dermis.

The release form of IAL-system is sterile gels placed in syringes of 1.1 ml or 0.6 ml. Having different volumes is very convenient. Depending on the indications and the amount of work, the cosmetologist will be able to choose a larger or smaller one. IAL-system is approved for use from 25 years of age. The time for a pronounced clinical effect from the use of this drug is 2-3 months.

The IAL-system is used to reduce geriatric changes. It can also be used for preventive purposes, especially after frequent exposure to direct sunlight. Thanks to biorevitalization with this product, it is possible to achieve excellent hydration, increase turgor, smooth out fine wrinkles, improve complexion, and provide a slight lifting effect. But this drug does not remove pigmentation, does not even out deep wrinkles, or corrects the shape of the face.

Advantages

1. native unmodified hyaluronic acid;
2. the effect is noticeable within 2-3 days after the manipulation;
3. different volumes of syringes;
4. reduces the severity of geriatric changes;
5. provides a high level of hydration;
6. evens out facial tone.

Flaws

1. Does not cope with pigmentation and deep wrinkles.

Teosyal Meso Expert

Rating: 4.7

Biorevitalizant Teosyal Meso Expert belongs to the Swiss company Teoxane. It contains hyaluronic acid at a concentration of 15 mg/ml. You can also find a large range of other valuable components in the composition, including vitamins, minerals, amino acids and antioxidants. This filler relieves inflammation, promotes regeneration, activates metabolic processes, and has an antioxidant effect.

Teosyal Meso Expert is an injection solution in a syringe (3 ml) placed in a cardboard box. On average, 2-3 sessions are recommended over 2-4 weeks. To consolidate the positive result, additional maintenance sessions are performed once every 2-3 months. Injections are made superficially. The drug can be used by clients over 25 years of age.

Consumers share that after procedures with Teosyal Meso Expert, the elasticity and firmness of their skin noticeably increases. The product perfectly moisturizes and tones. After 2-3 sessions, the skin looks very fresh, and small folds and grooves of the skin do not spoil the overall impression. After such injections, complexion improves and hyperpigmentation decreases. However, this product will not cope with deep wrinkles.

Advantages

1. well thought out, multi-component composition;
2. increases skin turgor and hydration;
3. makes the face fresh, radiant, with an even tone;
4. copes with shallow grooves and folds of the skin.

Flaws

1. does not cope with deep wrinkles.

Restylane Vital

Rating: 4.6

The Swedish cosmetics company Q-Med produces the biorevitalization drug Restylane Vital. Its active ingredient is HA of non-animal origin in a concentration of 2%. The composition is strong thanks to a special patented system. Restylane Vital perfectly fights the first geriatric changes, providing high-quality, deep hydration.

Restylane Vital is sold in a 1 ml syringe, packaged in a cardboard box. The composition contains lidocaine, which provides an analgesic effect. It is primarily used in areas where the first wrinkles often appear, as well as where the skin easily loses its elasticity. Restylane Vital is well suited for all skin types and all ages. The maximum result is achieved after completing 2-4 procedures. Each of them is performed once every 20 days.

Since Restylane gel is denser than its analogues, it cannot be injected onto the skin areas around the eyes and neck. The skin there is thin and this can take a very long time for the resorption of papules. A sustainable clinical effect after manipulation can last for 6-9 months. Fabrics receive a full amount of moisture. The contours of the face and neck are improved. Post-acne marks and wrinkles cease to be noticeable.

Advantages

1. highly concentrated HA;
2. suitable for all skin types and all age groups;
3. You can enjoy improvements for up to 6-9 months;
4. moisturizes, increases turgor;
5. smoothes wrinkles and acne marks;
6. makes the contours of the face and neck clearer.

Flaws

1. Not suitable for the eye and neck area.

NucleoSpire Revitalizing Complex B

Rating: 4.5

The Russian manufacturer Mesopharm produces the biorevitalizant NucleoSpire Revitalizing Complex B. It contains unstabilized HA of biosynthetic origin in a concentration of 18 mg/ml. The drug also contains vitamins, minerals and amino acids. This biorevitalizant perfectly restores cellular metabolism, improves tissue trophism and collagen production.

This drug from Mesopharm comes as a sterile filled 1.3 or 2.0 ml syringe with two needles included. This product is approved for use for any skin type from 30 years of age. Administration techniques: median nappage, micropapules, single injections. Already after the first procedures, positive dynamics are noticeable and they persist for 5 months.

This biorevitalizant tightens the skin, makes it elastic, and restores the contour of the face. The drug has high biocompatibility, rarely causes allergic reactions and does not require long-term rehabilitation. Papules usually resolve within 2-3 hours. The face immediately becomes fresh, its tone is evened out. And after 5-7 days the maximum cosmetic effect is observed.

Advantages

1. biorevitalizant with an exclusive formula;
2. Suitable for all skin types;
3. papules resolve quickly;
4. does not require a serious rehabilitation period;
5. increases turgor, eliminates sagging;
6. evens out the complexion and makes it fresh;
7. copes with fine wrinkles, hyperpigmentation, post-acne marks.

Flaws

1. not identified.

Viscoderm 1.6%

Rating: 4.4

The Italian drug Viscoderm 1.6% contains 16 mg of hyaluronic acid. It is obtained by biofermentation from natural raw materials. Since there were no chemical modifications during production, this drug has high biocompatibility and is well accepted by the human body. Viscoderm 1.6% is recommended for biorevitalization from 35-40 years of age.

Each package of Viscoderm 1.6% contains 1 glass syringe (1 ml). Its contents are sterile and, when administered, do not cause unwanted reactions in the body. The drug is suitable for both the face and body. The depth of insertion and technique may vary. It is recommended to conduct an intensive course - 4 sessions with breaks of 14 days. And then maintenance procedures once every 4 weeks.

The positive result from the use of Viscoderm 1.6% lasts for 8-9 months. Everything is individual, but on average, papules disappear after the procedure within 3-5 days. The skin becomes radiant and hydrated. Small folds and grooves on the skin are smoothed out. The skin texture becomes perfectly smooth. Post-acne elements are eliminated, atrophic scars and stretch marks are corrected.

Advantages

1. well accepted and tolerated by body tissues;
2. can be used both on the face and body;
3. the results of the procedures last for 8-9 months;
4. makes the skin moisturized and radiant;
5. smoothes out small folds and grooves on the skin.

Flaws

1. papules disappear within 3-5 days.

Rehabilitation period

Depending on the drug, the rehabilitation period after peptide biorevitalization lasts from one to several days. Small papules may form at the injection sites, which resolve fairly quickly. There may be redness for several hours after the procedure. Sometimes bruises and swelling, small nodules form. Minor pain is also considered normal. The appearance of any symptoms is a reason to consult a doctor for advice.

also important to adhere to the following post-injection recommendations for a period, the duration of which is determined by the doctor:

• do not apply decorative cosmetics to the treated area;
• Do not touch your face with your hands until the puncture sites heal;
• peeling, microdermabrasion and other aggressive procedures are prohibited;
• you should not visit solariums, baths, swimming pools;
• exposure to ultraviolet radiation should be avoided;
• refrain from intense physical activity.

As for the duration of the drug’s effect, you need to undergo several procedures to consolidate the result. The effect lasts from 6 months to 2 years, depending on the chosen product.

The best drugs for biorevitalization from Asia

Some cosmetologists choose products from Korea. They are valued for their rich, multi-component composition and long-lasting positive results after the procedure. Such drugs may differ in the concentration of HA, as well as other characteristics.

Yvoire Hydro

Rating: 4.9

The cosmetology department of the Korean company LG has developed a biorevitalization drug Yvoire Hydro. It is based on stabilized HA, presented at a concentration of 20 mg/ml. Thanks to this, this biorevitalizant is responsible for intensive hydration and leveling of the relief. With it, the face rejuvenates and begins to shine.

Yvoire Hydro is sold in 1 ml syringes. They are filled with a plastic gel with low density. It is easily distributed in the dermis, smoothing out the relief of the face, eliminating fine wrinkles, and also prevents early geriatric processes. This drug implies that the therapeutic course will include 3 biorevitalizations. There are 2 weeks between each new session.

Yvoire Hydro ensures that positive results are maintained for 12 months. Thanks to biorevitalization with this product, it is possible to eliminate shallow wrinkles between the eyebrows, around the eyes and mouth. The use of this drug also guarantees deep hydration. After a set of procedures, the face becomes radiant and has a beautiful, even tone. Papules after Yvoire Hydro go away very quickly.

Advantages

1. High molecular weight HA with a concentration of 20 mg/ml;
2. Only 3 injections are needed;
3. You can enjoy the results throughout the year;
4. short rehabilitation period;
5. fabrics receive high-quality moisture;
6. Effective elimination of fine wrinkles.

Flaws

1. not identified.

Mesoheal +

Rating: 4.8

A brand from South Korea, Koru Pharmaceuticals, has developed a very effective drug - Mesoheal +. It is enriched with unstabilized HA at a concentration of 25 mg/ml and with a molecular weight of 1500 kDa. Mesoheal + injections are safe and low-traumatic. After performing biorevitalization, you can count on a dynamic rejuvenation effect that improves the quality of the skin.

Mesoheal + can be purchased in 2.5 ml syringes. The injections are made shallow. There is a 1 cm gap between injections. During injection, various techniques can be used. Biorevitalization is recommended to be carried out once every 14 days. The main course should include 6 procedures, and the supporting one - 4. The course is prescribed individually by a cosmetologist.

According to reviews, after biorevitalization with Mesoheal +, the skin is quickly and maximally moisturized, and its elasticity returns. This biorevitalizant smoothes wrinkles, regulates the formation of melanin, has a lifting effect, narrows pores, eliminates inflammatory processes, and normalizes the functioning of the sebaceous glands. Papules on the face resolve quite quickly, but on the neck and décolleté this process can take 5-7 days.

Advantages

1. safe and low-traumatic injections;
2. provides quick and maximum hydration;
3. evens out skin tone;
4. smoothes out fine wrinkles;
5. eliminates inflammatory processes.

Flaws

1. Swelling in the injection sites lasts up to 7 days.

Aquashine HA

Rating: 4.7

The Korean brand Caregen has developed an effective drug Aquashine HA. It combines 2 types of hyaluronic acid, the concentration of which reaches a total of 15 mg/ml. It also contains a complex of vitamins, minerals, amino acids and coenzymes. Such a rich composition quickly solves the problem of skin withering caused by geriatric processes.

Aquashine HA is sold in 2 ml syringes. Focusing on the initial condition of the patient’s skin, the cosmetologist selects the necessary injection technique. With the classical technique, the injection depth usually reaches 2-4 mm. Biorevitalization with this Korean drug most often includes 2 to 5 procedures, performed with a break of 15-20 days.

From the reviews it follows that the result appears approximately two weeks after the injections. This product does not contain animal proteins, so there is no need to further test it to determine the likelihood of an allergic reaction. Aquashine HA provides prolonged skin hydration with the creation of a hydro reserve. It guarantees evenness of tone and texture, and skin radiance. After biorevitalization with this remedy, the manifestations of rosacea and hyperpigmentation are reduced.

Advantages

1. more than 50 active components in the composition;
2. does not require preliminary allergy testing;
3. the skin becomes more elastic, smooth and radiant;
4. smoothes out small wrinkles;
5. prolonged skin hydration.

Flaws

1. papules from injections take quite a long time to resolve.

Possible side effects

What consequences may arise as a result of biorevitalization:

• swelling of the hands;
• hematomas at puncture sites;
• non-absorbable lumps from injections (papules);
• soreness.

The cause of these phenomena may be a violation of the technique of administering the active substance, an incorrectly selected volume, or the individual characteristics of the body. If the components of the drug do not cause allergies, adverse reactions, as a rule, go away quickly.

Hand restoration and care after biorevitalization

The specialist who carries out the procedure for laser biorevitalization of the hands must inform the patient about how soon the recovery period will end and when it is possible to return to a normal lifestyle, what reactions of the body during the rehabilitation period are normal, and what should be of concern.

Condition immediately after biorevitalization

Bruising, swelling and loss of arm mobility are common symptoms after the procedure. Standard medical recommendations in this case: apply ice to your hands and maintain hygiene. Under no circumstances should the skin be exposed to sunlight. After the anesthetic wears off, pain may occur. You need to tell the specialist who performed the laser biorevitalization of the hands about them so that he can assess the condition: is it normal or complications have arisen.

The best drugs for biorevitalization from the USA

The best salons and beauty salons usually give preference to American drugs. Many experts consider them highly effective and extremely safe.

Meso-Xanthin F199

Rating: 4.9

The injectable drug Meso-Xanthin F199 was developed by the American company ABG Lab. It has a multicomponent composition, including: fucoxanthin, high molecular weight hyaluronic acid, vitamins, minerals, amino acids, antioxidants. This biorevitalizant effectively corrects early geriatric signs on the face, neck, and décolleté. It is suitable for clients aged 25-30 years.

This American cosmetic product is available in 1.5 ml syringes. The package is opened immediately before the procedure in the cosmetologist's office. One syringe is usually enough to treat three main areas. On the face, injections are made to a depth of 4 mm. When injecting on the neck, the depth should not exceed 2 mm. Between injections make indentations of 0.8-1.0 cm.

Women share that hyperemia, swelling or other traces of injections cease to be noticeable in 1-3 days. To consolidate a positive result, the course should include 4-6 sessions with breaks of 7-14 days. The results of such biorevitalization can last for 12 months. After a full course, you can forget about facial wrinkles, dryness, dehydration, enlarged pores, and post-acne.

Advantages

1. complex, complex composition;
2. after a full course, the result lasts for 1 year;
3. facial skin is noticeably tightened;
4. manifestations of rosacea and hyperpigmentation are reduced;
5. mimic wrinkles are eliminated.

Flaws

1. Individual intolerance to individual components is possible.

Juvederm Hydrate

Rating: 4.8

The American brand Allergan has developed the drug Juvederm Hydrate. It contains not only hyaluronic acid, but also the antioxidant mannitol. The latter protects HA from dynamic breakdown, and also protects dermal cells from the negative effects of free radicals. This product effectively moisturizes and rejuvenates the skin. The drug is optimally suited for persons 25-35 years old.

The optimal course of use of Juvederm Hydrate is 3 procedures. Each of them is done with a break of 15-20 days. After such biorevitalization sessions, you can enjoy the results for 12 months. In case of severe dehydration or associated negative factors (tobacco smoking, overwork, age over 35 years), the procedure is recommended to be performed once every 6 months. Juvederm Hydrate is a safe and low-impact product.

With subcutaneous administration of this American drug, you can achieve smoothing of wrinkles, increased tone, and a slight lifting effect. This remedy slows down the aging process. Papules, swelling or other negative effects after such procedures usually disappear within 2-5 days. For people over 35 years of age, this drug is less effective. For more mature skin, it can be used as an adjuvant in complex contouring.

Advantages

1. the presence of mannitol in the composition;
2. Three procedures are enough;
3. the effect lasts for 12 months;
4. deeply moisturizes the skin;
5. returns radiance, elasticity, tone to the skin;
6. smoothes out small wrinkles.

Flaws

1. weak for people over 35 years of age.

Meso-Wharton P199

Rating: 4.7

The new generation injection drug Meso-Wharton P199 was developed by the American company ABG Lab. It contains: a unique regulatory oligopeptide, high molecular weight hyaluronic acid, as well as a large set of other active components. This cosmetic product is intended for intensive restoration and “rejuvenation” of the skin of mature individuals over 40 years of age.

Meso-Wharton P199 is available in 1.5 ml syringes. Usually this volume is enough to treat the face, neck, and décolleté area. If clients are already 40-50 years old, then the intensive course for them should be 4-6 procedures. Once a week the drug is administered 4 times, and then it is injected 2 more times with an interval of 2 weeks. To consolidate the effect, biorevitalization can be carried out once every 2-3 months.

Women speak well of this drug and share that Meso-Wharton P199 increases the density, elasticity and level of hydration of the skin, and smoothes the microrelief. With a course of use of this drug, the contour of the oval of the face noticeably improves, a lifting effect is achieved, and the severity of hyperpigmentation is reduced. Papules after administration of this remedy usually resolve within 3 days.

Advantages

1. unique, multi-component composition;
2. perfectly corrects age-related changes in the skin;
3. suitable for preventing “withering”;
4. increases the level of skin hydration;
5. visibly smoothes wrinkles, including deep ones.

Preparation for the procedure

3-4 days before the proposed peptide biorevitalization, it is recommended to refrain from:

• drinking alcohol and smoking;
• tanning;
• taking anticoagulants, painkillers and sleeping pills.

You should not plan the procedure during menstruation, otherwise there is a risk of a large number of bruises and hematomas.

Those who are prone to herpetic rashes should take Acyclovir 3 days before biorevitalization.

And if you want to cleanse your face, then it must be done at least two weeks before injection rejuvenation.