When choosing a drug for contouring or biorevitalization, visitors to beauty salons and clinics are guided by various factors: price, composition, popularity of the filler, as well as reviews about it. Revaness brand products have a good reputation. Many cosmetologists enjoy working with a wide range of these products, and patients are delighted with the results. True, the use of these drugs is still accompanied by some nuances. Find out what the advantages and disadvantages of Revanesse fillers are and who they may not be suitable for.
General characteristics
These products are produced by the Canadian company Prollenium Medical Technologies, which specializes in the creation of biorevitalizants and preparations for contouring. The line includes Revanesse and ReDexis fillers, as well as injectable serums - Skin Rejuvenating for skin rejuvenation and Lypoless for reducing fat deposits and simultaneously tightening the dermis. The official distributor of these products in Russia is the Best Aesthetics company. Revanesse fillers contain only hyaluronic acid of varying concentrations. ReDexis also contains dextranomer, which stimulates collagen synthesis.
A few years ago, in addition to hyaluronic acid, Revaness contained additional components: monohydrogen phosphate, lactic acid, etc. Since then, the composition has changed. Representatives of the Best Aesthetics company emphasize: now there is nothing in Revanesse fillers except hyaluronic acid. However, disputes between cosmetologists on this topic are still found on thematic forums.
Types of fillers
The line of fillers and biorevitalizants consists of 7 drugs:
- Revanesse Pure . It is a transparent gel. 1 ml of Revanesse Pure contains 14 mg of hyaluronic acid. Suitable for moisturizing and rejuvenating the skin of the face, neck, hands. Increases skin elasticity and eliminates signs of aging. Revaness Pure is injected into the superficial layers of the dermis, as it is a biorevitalizant. The course usually consists of one procedure over 4 months.
- Revanesse . Contains 25 mg of hyaluronic acid per 1 ml. Used to fill superficial and medium-depth wrinkles on the face, neck, and hands. Smoothes nasolabial folds and crow's feet, corrects the area between the eyebrows. Revaness injections are intended for the middle layers of the dermis. The duration of action is about six months. The gel completely dissolves within 8–9 months.
- Revanesse Ultra . Composition: high viscosity hyaluronic acid in a volume of 25 ml/mg. The gel is made using the Thixofix cross-linking process. Thanks to the patented technology, a thick, long-lasting drug was obtained: Revaness Ultra dissolves in the body from 9 to 12 months. Suitable for smoothing medium and deep wrinkles, lip contour correction and intimate plastic surgery. The gel is injected into the medium-deep layers of the skin.
- Revanesse Contour . Highly viscous drug, the concentration of hyaluronic acid is 25 ml/mg. Used for contouring and adding volume to the cheeks and chin, lip augmentation, and figure correction. Revaness Contour naturally dissolves within 1.5 to 2 years.
- Revanesse Kiss (formerly LIPS) . Created to increase volume and correct lip shape. eliminating wrinkles near the mouth. The concentration of hyaluronic acid is 25 ml/mg. Revaness Kiss filler dissolves within 9–12 months.
- ReDexis . 1 ml of the drug contains 25 mg of hyaluronic acid and dextranomer. Regenerates the skin, fights medium and deep wrinkles. Stimulates collagen production. Redexis is administered subcutaneously and resolves within about 1.5 years.
- ReDexis Ultra . Contains hyaluronic acid in the same concentration - 25 mg/ml, and the amount of dextranomer here is doubled: 50 mg/ml. Eliminates wrinkles and folds, activates the synthesis of your own collagen. Dissolves in the body for up to 2 years.
Indications, effectiveness of use
The Revanesse collection covers almost the entire range of age and aesthetic problems. With the help of Canadian fillers and biorevitalizant you can:
- smooth out folds and wrinkles - from superficial to deep;
- eliminate crow's feet, nasolabial and glabellar furrows;
- raise the corners of the mouth;
- increase lip volume, remove contour asymmetry;
- improve the proportions of the facial oval;
- correct the shape of the cheekbones, cheeks, chin;
- moisturize and refresh the skin;
- make the skin more elastic and elastic;
- improve and even out complexion;
- rejuvenate your neck and arms.
Biorevitalization and contour plastic surgery have age restrictions: the lower limit is 18 years. However, Revanesse injections are usually chosen by women after 30. It is at this age that the skin begins to experience a lack of moisture, which affects the entire appearance. Revanesse Kiss fillers are also popular. Redexis and Redexis Ultra are optimal for women over 35 years of age.
Price
Revanesse can only be purchased by cosmetologists, so information on the cost of Revanesse is not publicly available. You can find out the price in online stores only after registration, which includes confirmation of specialized medical education. Some sites indicate an approximate cost of about 9–10 thousand rubles per package. As a rule, these are 2 syringes, each of which contains 1 ml of the drug.
Advice. To avoid buying a fake, you should buy Revaness from an official distributor of Canadian fillers. Best Aesthetics company offers delivery and pickup of products.
FDA why it matters
Revanesse® is one of 5 fillers in Russia approved by the FDA
Unique formula
- Exceptionally high quality HA
- Patented homogenization technology produces round, smooth and spherical HA particles
- Optimal cross-linking using exclusively long-chain hyaluronic acid (HA) molecules, therefore requiring less BDDE coupling agent
- Dialysis for 7 days to neutralize pH, achieve appropriate osmolality and remove residual BDDE binder and toxins.
- The finished HA gel is packaged in 1.0 ml syringes and sterilized with steam (sterilizer)
- Strict quality control throughout the entire production process
Round and smooth HA particles reduce the likelihood of an inflammatory reaction
Revanesse® fillers are formulated to the highest standards of purity.
Thanks to the use of high molecular weight HA chains, unique homogenization and binding technologies (Thixofix®), very little BDDE is required for the production of the drug.
Thus, the final degree of modification of Revanesse® does not exceed 2%
This is a guarantee of a successful procedure - no swelling and undesirable effects
Revanesse® fillers are created using Thixofix® HA crosslinking technology. The essence of the technology is that it takes as a basis such a property of substances as thixotropy. This property represents the ability of a substance to reduce viscosity (liquefy) under mechanical stress and increase viscosity (thicken) at rest.
Thanks to this technology, a cosmetologist can inject highly viscous gels using a syringe with a thin needle, without causing degradation of the modified particles.
Thixofix® technology ensures smooth and precise injection of the drug into the patient’s soft tissues
Elasticity (G') of Revanesse® fillers
G' reflects the elasticity characteristics (stiffness or resistance to deformation) of the HA gel or its ability to regain its shape after deformation (injection process)
Revanesse® products range from low G' for greater softness and ductility to high G' for greater rigidity and resistance to deformation.
The Revanesse® product line ranges from low viscosity products (thinner) to high viscosity products (less thinner) to create the desired level of volume at varying injection depths on standard areas of the face (viscosity is a measure of resistance to flow (density) under shear deformation in injection process)
revanesse® products are characterized by low levels of water absorption after injection
Water absorption is extremely important for the doctor's confidence in the implantation result.
Average swelling degree (ml/g) for Revanesse® products - 3.7
Adaptability to dynamic muscle contractions is essential for varying injection depths on standard injection areas of the face
Cohesiveness reflects an understanding of how well the gel adapts to/resists dynamic muscle contractions
revanesse® products offer optimal cohesiveness after injection
Cohesiveness is measured by weighing drug drops
Average Drop Weight (mg) for Revanesse® products: 27
Description of the procedure
One of the most important decisions, on which the result largely depends, is the choice of clinic and doctor. The medical institution must have a license and permits to provide such services. The same applies to the doctor.
Only a qualified specialist who has mastered the appropriate facial correction technique, has a certificate of completion of courses and has worked directly with these fillers can perform Revanesse injections.
The Best Aesthetics company conducts seminars and master classes for cosmetologists. The schedule can be found on the official website of the distributor.
Preparation
The first visit to the clinic is an occasion to meet the doctor and receive a detailed consultation. Any rejuvenating or corrective procedure using Revaness or other hyaluronic acid preparations is preceded by a preparatory period. It can last several days or weeks, as it includes the following stages:
- Examination by a cosmetologist. Discussion of options for solving problems, choosing a suitable product from the Revaness line.
- The patient undergoes a medical examination. The doctor must have a report on your state of health. This will reduce the risk of adverse reactions and side effects after administration of Revanesse.
- Preparing the patient for the procedure in advance:
- quitting smoking and alcohol;
- stopping taking certain medications - aspirin, antibiotics, anti-inflammatory drugs. You can't do this on your own! Be sure to consult your doctor so as not to harm your body by interrupting therapy;
- refusal to visit the beach, sauna and bathhouse.
It is advisable to begin following these recommendations at least 3-4 days before your scheduled Revaness injections. You will know the exact date in advance: the doctor will ask you to sign an agreement on the provision of cosmetic services and together with you will choose the day and time. Try not to have it during your period.
There are no direct contraindications to the use of Revanesse, however, during menstruation, women’s pain threshold decreases (you will understand what we are talking about if you have at least once tried to do hair removal or other painful procedures during “these days”). Also, on the eve of or during menstruation itself, blood clotting may be impaired. This is fraught with injury to blood vessels and the appearance of hematomas at the sites of Revanesse injections.
A day before the procedure, you need to stop applying makeup to your face.
Injection technique
The procedure using Revaness lasts at least 10–15 minutes. If the doctor needs to treat a large area, the time will increase accordingly. The introduction of a filler or biorevitalizant proceeds approximately according to the following scheme:
- The doctor cleans the patient's skin and then disinfects it. Revanesse, like other similar drugs, must be injected under sterile conditions!
- If necessary, the specialist will use local anesthesia. It is believed that it reduces the effectiveness of fillers, but for particularly sensitive women who cannot bear even such pain, this may be a solution.
- The doctor opens the Revaness package so that the patient sees its original integrity. Before use, the drug should be kept at room temperature for half an hour. The syringe with gel and needles included in the kit are designed for single use. Otherwise, there is a risk of complications.
- Next, the specialist begins performing Revaness injections. To begin, the cosmetologist will press the plunger of the syringe so that a drop of gel appears at the tip of the needle.
- Revanesse can be administered using different techniques. The doctor will choose the appropriate one and also determine the depth of the injection. For administration, it is recommended to use 27G, 30G or 32G needles (for different drugs).
- At the end of the procedure, the doctor disinfects the skin again and explains in detail how to care for the treated area.
Healing period
Even spot injections of Revaness are stressful for the skin, so it reacts accordingly: it may bruise, become red or swollen. Pain and itching are possible. These and other side effects disappear within a few days, or at most within a week. If not, the patient should be wary.
The following symptoms should be the reason to contact the clinic:
- hematomas and swelling that do not go away for a long time after Revanesse injections;
- loss of sensitivity of the skin;
- discoloration of the dermis;
- a feeling that the Revaness fillers have not been distributed under the skin - when massaging the skin, compactions and nodules are felt;
- fibrosis (overgrowth of connective tissue);
- increase in temperature, etc.
If the doctor has done everything flawlessly, the further development of events largely depends on the patient’s behavior. The rules of care after Revanesse injections are simple:
- for at least 12 hours after the procedure, do not touch the treated areas with your hands, protect them from the sun, overheating and hypothermia;
- if the doctor gave Revaness injections in the face area, forget about cosmetics for at least a day;
- Do not visit the sauna and bathhouse for 3 days and the solarium for a week;
- reduce physical activity and sports;
- Follow a healthy lifestyle to prolong the effect of the injections.
How to remove the drug from the body
An unsatisfactory appearance within 2 weeks after the administration of Revaness is evidence that the drug is still “settled” in the body. But if the result is not satisfactory even after this time, the patient may think about returning everything as it was.
Regardless of what led to such a decision - the inept actions of the doctor, complications after the procedure, or rejection of one’s own new appearance - there are several ways to remove Revanesse.
Since the main component of fillers and biorevitalizant is hyaluronic acid, the first aid is enzyme preparations based on hyaluronidase: Longidaza, Lidaza or something else.
They are used only if the patient is not allergic to the active substance. Physiotherapeutic procedures will help minimize the effect of Revaness: microcurrents, darsonval. Also, the remaining hyaluronic acid comes out along with sweat secretions. To do this, you can actively engage in sports, visit a sauna or bathhouse, and drink hot drinks (not alcoholic).
Dextranomer microspheres in ReDexis stimulate collagen synthesis at the injection site
The main ingredient of Redexis - positively charged dextranomer microspheres - consist of biocompatible cross-linked glucose molecules.
These microspheres attract negatively charged glucosaminoglucan and elastin to the injection site, facilitating the synthesis of new collagen. They then begin to join together to form the basis for new collagen. This new collagen remains at the injection site, providing a natural tightening to the skin long after the HA breaks down and is released. The end result is increased volume at the injection site, as well as a long-term, more natural appearance than other filler brands.
First injection of ReDexis
New collagen is formed after ReDexis treatment
Second injection of ReDexis
Repeated administration after 2-3 weeks leads to a significant increase in collagen synthesis
Precautionary measures
To avoid possible complications from Revaness, you should not give injections of hyaluronic acid:
- during pregnancy and breastfeeding;
- patients under 18 years of age;
- cancer patients;
- with a tendency to form hypertrophic scars;
- combining Revanesse injections with laser treatment, chemical peeling;
- for inflammatory skin diseases - acute and chronic;
- if the patient has individual intolerance to hyaluronic acid;
- with multiple allergic reactions;
- if the patient has a history of autoimmune diseases, Revanesse is strictly prohibited;
- for damage to the skin - scratches, abrasions, etc.
Attention! Contraindications to the use of Revaness are also acne, herpes, streptococcal infection, bleeding disorders, colds and viral illnesses.
In addition to these prohibitions, there are other nuances of using drugs from the Revanesse line. During work, the cosmetologist must ensure not only sterility, but also the safety of the procedure. precautions for this
- Revaness should not be injected into the eyelids, bones, tendons, muscles and ligaments;
- these drugs are not used to increase breast volume;
- Revanesse is dangerous to inject into areas where there are already other fillers. Unpredictable reactions are possible, since there are no reliable clinical studies on this topic;
- the introduction of Revaness into a blood vessel can provoke an embolism (blockage);
- If during the procedure the skin becomes white or pale, you should stop the injection immediately. This area should be massaged until the dermis returns to its original color;
- Revanesse must be stored at temperatures from +2 to +25 °C.
Advantages and disadvantages
Revaness preparations have many significant advantages and disadvantages:
- hypoallergenic;
- efficiency;
- comfort at work, which is confirmed by many cosmetologists;
- prolonged effect - Revaness dissolves in the body for up to 2 years;
- range of drugs for different purposes, etc.
The disadvantages of Revanesse include the high cost of fillers and the risk of side effects, in particular edema. This is especially noticeable in patients with sensitive, thin skin. In such cases, rehabilitation takes longer.
Since Revaness contains only hyaluronic acid, this distinguishes the drugs from some popular analogues. For example, Aquashine additionally contains peptides, vitamins and other substances, and Yalupro products are enriched with amino acids, etc. If we compare Revanesse with other fillers in terms of the cost of procedures, this brand will be in a fairly high price category. But the effect from it lasts quite a long time: from 8 to 18–24 months. But there is competition here too - approximately the same result (9-14 months) is promised by the filler manufacturer Otesaly.
Revanesse Pure
Revanesse Pure is a non-crosslinked hyaluronic acid (14 mg/ml) presented in gel form. Homogeneous and soft Pure gel is ideal for deep hydration, restoring firmness and elasticity of the skin. Revanesse Pure can be used on the face, hands, décolleté and neck.
Revanesse Pure is equivalent to native HA, which provides deep skin nutrition. Thanks to its composition, the drug is ideal for the prevention of premature aging, as well as for deep moisturizing and biorevitalization of the skin.
Composition of Revanesse Pure
The main component of the product is thoroughly purified hyaluronic acid (there are 14 g of it here). It is diluted with phosphate buffer solution. The composition is distinguished by its monophasic structure. Due to its homogeneity, the product easily passes under the skin. The gel completely dissolves within 6-24 months.
What are the benefits of Revanesse Pure?
The drug is effective, you can see results after the first use. The manufacturer managed to develop a hypoallergenic formula. The product does not cause side effects or addiction.
This is a completely biocompatible drug. Infection is impossible, since synthesized HA is used here. The drug does not in any way affect the natural metabolism of tissues. The product will not go beyond the scope of application. The procedure for introducing the composition lasts only 15-20 minutes. The process affects only the top layer of dermal tissue. The introduction is carried out under anesthesia.
Opinion of cosmetologists
The vast majority of reviews that can be found on thematic forums are positive. There are cosmetologists who do not find a single disadvantage in working with Revaness.
The author of this review especially highlights Revanesse Contour.
According to another specialist, there are no drugs equal in effectiveness to the Revanesse Kiss filler.
At the same time, there are cosmetologists who are confused by the long-lasting side effect of using Revaness - swelling.
This specialist notes: Revanesse brand products are almost ideal, and long-term swelling in some patients is an individual characteristic of the body.
The author of this review agrees that over several years of work, Revaness has proven itself almost flawlessly.
Patient reviews
Patients also praise various drugs from the Revanesse line. The author of this review was pleased with how the filler removed nasolabial folds, as well as the duration of the result. Revaness Ultra was used for the procedure.
This girl also eliminated a similar problem with the help of Revanesse, entrusting the choice of the drug to her cosmetologist.
This review praises the biorevitalizant Revanesse Pure, especially since it did not cause severe side effects.
And here the patient is delighted with the result, but at the same time notes that the recovery period after Revaness injections was not entirely smooth.
Of course, the almost complete absence of negative comments about the experience of using the Revanesse line is not a guarantee that everything always goes perfectly. However, the chances of this happening are quite high. The quality and effectiveness of Canadian fillers and biorevitalizant have made Revaness a popular product in many clinics and medical centers.
Research results
Revaness – evidence-based fillers
A multicenter, double-blind, randomized, split-face study was conducted to evaluate the safety and effectiveness of Revanesse® Ultra™
Among patients who did not violate the protocol, there was a difference between Ultra and comparator based on igai and pgai efficacy scores at 24 weeks postprocedure. The percentages reporting “much improvement” or “very much improvement” were 59.2% and 44.4% for Ultra and 47.2% and 30.6% for comparator on the iGAI and pGAI scales, respectively.
Among the total patient sample, 28.3% fewer patients reported injection site pain with Ultra compared to the other drug.
Among the total patient sample, 14.1% fewer patients reported TEAEs following a procedure performed with Ultra compared to the other agent.
