Aprilline is a new generation Swiss drug for contouring.

General information about the drug

Apriline is a new generation dermal filler. The line of filler products includes plastic, homogeneous monophasic gels based on hyaluronic acid. It contains 3 types: Normal, Forte and Hydro . They differ in the concentration of hyaluron, therefore they are designed to solve various problems. Apriline also produces a series of mesotherapy products. The meso line (apriline skin and age) is unique, it includes complex integrated vitamin-peptide products for reconstructive mesotherapy.

Apriline preparations are produced in Switzerland. The company's specialists have been studying the properties and effects of hyaluronic acid on the skin for more than 50 years. Products from the Swiss company Suiselle have proven themselves to be excellent for eliminating signs of aging and restoring elasticity. All this can be achieved thanks to a thoughtful composition.

The consistency of the drug is like a dense gel, so it is firmly fixed in tissues that have lost their elasticity, gives them the correct shape and becomes a frame. The risks of Apriline filler migration are minimal.

In cosmetology, Apriline is now considered the most popular filler; it is equally suitable even for sensitive skin. The product does not provoke allergies, has a good survival rate and the ability to quickly obtain the expected effect.

The uniform structure of the drug allows you to fill both small and deeper wrinkles of various types - age-related, facial, static, thereby restoring elasticity to the skin. The drug does not provoke edema, since there are no large particles in the composition. The skin remains smooth and looks healthy.

Advantages

Beauty injections with Apriline have a large number of advantages:

• sufficient viscosity of consistency to achieve the desired filling of wrinkles;
• convenient and comfortable procedure;
• purity of the composition, ensuring safety and sterility;
• long-term retention of results;
• minor complications occur in no more than 5% of cases.

Despite the rarity of side effects, clients should be aware of the consequences the drug may cause. These include:

• hematoma and swelling - if the needle gets into the vessel, they disappear after a week;
• pain in people with high sensitivity of the skin and a low pain threshold - the specialist may suggest the use of an anesthetic;
• inflammatory process - develops in the event of a violation of disinfection - is treated with anti-inflammatory drugs;
• gel displacement - occurs when the composition is introduced too deeply or superficially;
• hypersensitivity reaction – in case of individual intolerance to the composition of Apriline.

Product line, purpose

There are 3 main drugs in the filler series. Their differences are in the concentration of hyaluronic acid, and therefore in the strength of the effect on wrinkles and areas of use.

Apriline Normal

Means for contouring, concentration of active component 23 mg/ml. It is intended for surface use, the viscosity is 500 thousand mPa. The Normal line gel improves elasticity and skin turgor, helps smooth out facial wrinkles on the forehead, in the nasolabial triangle, and in the periorbital area. Apriline Normal is also used to improve contours and add volume to lips. The results last for 6 - 10 months.

Apriline Forte

The consistency of this filler is denser and amounts to 1 million mPa, the concentration of hyaluron is the same - 23 mg/ml. The product from the Aprilline Forte line is more suitable for filling deep folds and wrinkles, pronounced correction of the oval of the face, restoring the volume of the cheeks, cheekbones, chin, and for lip augmentation. The composition is introduced into the middle or deep layers of the skin.

The effect is comparable to the most expensive and well-known fillers in cosmetology. The result lasts from 8 to 12 months.

Apriline Hydro

This is a biorevitalizant that is made with hyaluronic acid. Its concentration is 18 mg/ml. The drug is used to activate the natural rejuvenation of the skin on the neck, face, décolleté and hands. Apriline Hydro helps fight wrinkles, improves skin tone and elasticity, and prevents premature aging of the skin. The product is injected into the surface layers, the effect lasts from 6 to 9 months.

Apriline meso line

1. Apriline age line. The regenerating lifting formula helps fight the pronounced manifestations of photoaging; it is characterized by a prolonged action.
2. Apriline skin line . This drug promotes intense hydration and corrects the onset of photoaging. Apriline skin restores cellular resources.

The advantages of Apriline meso are:

• unique balanced composition;
• high biomechanical accessibility of components;
• gradual release of peptides, trace elements, amino acids and vitamins;
• prolonged action;
• stimulation of the natural activity of skin cells.

SkinPlus-HYAL are the first dense fillers with ideal plasticity.

Introduction
Today it is no longer possible to imagine cosmetology without injection procedures. For biorevitalization and contouring, the choice is increasingly being made in favor of preparations based on hyaluronic acid. This is due to many years of experience with them, good clinical results and safety of their use.

Modern cosmetologists and their patients have formed their own requirements for fillers: safety, plasticity, ease of administration, the ability to preserve and retain their shape for a long time. The South Korean concern BioPlus has developed a special production technology that made it possible to obtain just such a filler.

Technologies

BioPlus Co., Ltd was established in May 2003 in Korea. The corporation has focused its research and development in studying the ability of tissues to repair, regenerate blood cells, as well as in the anti-age direction and has been a leader in bioengineering since its founding. Experience and technological skill allowed her to create a line of unique biorevitalizants and fillers based on hyaluronic acid that meet all modern requirements and standards.

MCL* Technology is a technology for multi-level cross-linking of hyaluronic acid, creating preparations with symbiotic characteristics in terms of viscoelastic properties, plasticity and the ability to retain a given shape.

MCL Technology is a filler production method developed specifically for the climate of Europe and Canada. An ideal solution for edema-deformation and asthenic types of aging.

A distinctive feature of this technology is the ability to increase the density and size of hyaluronic acid microgranules without compromising the plasticity of the material and its easy distribution in tissues after administration.

Safety

The safety of the drugs is confirmed by various patents of the manufacturer - BioPlus Co., Ltd, as well as RU for a medical device No. RZN2016 / 4999 dated November 11, 2016, valid in the Russian Federation.

Preparations from the SkinPlus-HYAL line are designed to correct deficiencies in soft tissue of any volume, model the created architectural form, and maintain a given shape under any mechanical influence. The SkinPlus-HYAL line is represented by five products that differ in gel density and are designed to solve different aesthetic problems.

SkinPlus-HYAL 100* Hard-1

The densest gel in the line, which has high viscoelastic properties and high cohesiveness, low mobility along with excellent sculpting properties. The effect lasts up to two years. The drug is suitable for supraperiosteal administration for the purpose of volumetric correction and restoration of lost volumes.

Indications for use:

• modeling of the zygomatic zone,
• correction of the mandibular angle,
• improvement of the contour of the lower jaw,
• modeling the shape of the chin,
• formation of a clear oval face.

SkinPlus-HYAL 100* Hard-2

A drug with high viscoelastic properties, but at the same time retaining the ability to model and smooth extrusion, which greatly simplifies the work of a cosmetologist. The effect lasts up to two years. Suitable for injection into the deep subdermal layers of tissue to restore volume, filling deep and moderate wrinkles and skin folds.

Indications for use:

• modeling of the cheek-zygomatic area,
• injection rhinoplasty,
• correction of nasolabial folds,
• correction of “marionette wrinkles”,
• modeling the shape of the chin,
• elimination of facial asymmetry,
• 3D facial modeling,
• filling defects associated with scars.

SkinPlus-HYAL 100* Semi Hard

Multizonal filler with medium viscoelastic properties, but high cohesiveness, which allows it to maintain its shape with little external force. This filler is suitable for injection into the middle layers of the dermis. Recommended for correcting tissue volume and wrinkles of varying severity.

Indications for use:

• filling medium and deep folds and wrinkles,
• replenishment of the volume of the temporal zone,
• correction of nasolacrimal and palpebromalar grooves,
• modeling of earlobes,
• correction of nasolabial folds,
• Correcting the shape of the lips and increasing their volume,
• correction of the perioral zone: labiomental wrinkles, “purse-string” wrinkles, raising the corners of the mouth.

SkinPlus-HYAL 100* Soft

A “soft” filler with low viscoelastic properties, but excellent plasticity, which will not be too fluid. This filler is suitable for injection into the middle or upper layers of the dermis to work with thin skin, delicate areas, filling superficial wrinkles, and improving the quality characteristics of the skin.

Indications for use:

• filling “purse-string” wrinkles,
• lip correction without pronounced volume,
• correction of wrinkle lines,
• correction of age-related changes in the hands.

SkinPlus-HYAL 60* Soft

This biorevitalizant is indicated for use:

• decreased skin tone,
• dehydrated skin,
• the first stage of correction of dermal wrinkles of various etiologies,
• superficial wrinkles due to skin dehydration,
• preparation and rehabilitation of the skin during superficial, medium and deep peelings,
• normalization of scarring processes in cases of post-acne, after chickenpox, injuries, stretch marks,
• preparation for sun exposure and skin restoration after intense sun exposure.

General contraindications to the injection of any fillers:

• inflammatory diseases in the acute stage,
• tendency to form hypertrophic and keloid scars,
• pregnancy, lactation,
• autoimmune diseases,
• hypersensitivity to the components of the drug,
• bleeding disorder,
• oncological and acute infectious diseases,
• feverish conditions,
• permanent fillers in the injection area.

Distribution

To buy SkinPlus-HYAL preparations and learn how to work with them, contact the exclusive distributor in the Russian Federation, Medex LLC: + 7 (499) 519‑01‑21, www.skinplushyal.ru

Author: Elena Shamanina, dermatovenerologist, Moscow.

Magazine: Appearance. Esthetic guide №3(31)

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Indications and contraindications

Due to the thoughtful composition and high effectiveness, as well as a large number of good reviews, Apriline is often recommended by professional plastic surgeons for contouring. This helps to quickly combat the signs of aging. Most often, Apriline is prescribed in the following cases:

• loss of natural firmness and elasticity of the skin;
• severe tissue swelling;
• persistent dark circles under the eyes;
• elimination of wrinkles of different origins and locations;
• rejuvenation of the skin, stimulation of natural cell regeneration.

The drug is completely safe for health, it copes well with its tasks even on sensitive skin, eliminating extensive changes.

It should be noted that there are contraindications for the drug:

• autoimmune pathologies;
• blood clotting disorder;
• age under 18 years;
• pregnancy and lactation;
• tendency to exhibit hypersensitivity to hyaluronic acid and its derivatives.

Administration zones

The scope of application of fillers is practically unlimited, but the drug must be administered carefully where nerves and blood vessels pass close. It is worth postponing the procedure if there is inflammation, peeling, or elevated temperature. The most popular places for injection of fillers:

• Nasolabial folds. The appearance of deep wrinkles is one of the first and noticeable signs of aging. It is impossible to correct such a defect with simple procedures using conventional cosmetics. Fillers will allow you to straighten the fold: one procedure is necessary to inject about 2-3 ml of filler into the surface layers of the skin.
• The area around the eyes. Fillers can also help eliminate facial wrinkles, crow's feet and correct bruises. Typically, about 1 ml is injected around the eye. To inject fillers, the Dorsummed clinic uses microcannulas, which makes the procedure safe.
• Lips. One of the simplest procedures. The patient chooses the required volume herself, but the cosmetologist gives recommendations to maintain the proportions of the face. Typically, 1 to 3 ml of filler are injected.
• Forehead. Deep transverse wrinkles are one of the most common age-related problems. Even young girls suffer from such defects due to genetics. The problem is solved quickly by injecting 1-2 ml of filler.

Rehabilitation period - do's and don'ts

The process of introducing filler is not a complex procedure. The drug is administered by a cosmetologist in accordance with the intended purpose. The injection site and layers of skin must be discussed in advance.

Difficulties with organizing and conducting almost never arise. First, the specialist examines the condition of the skin and identifies areas where the use of filler is required. Then, after special markings, injections are given. Their number is also determined by the procedure during the preliminary consultation and examination.

The duration is maximum 30 minutes. If necessary, surface anesthetics such as Novocaine or Lidocaine are applied before starting to relieve pain.

The results after the procedure are visible immediately; if side effects develop, they successfully disappear after 6–7 days without additional therapy.

The number of injections and repetitions will depend on the injection site and the type of gel chosen:

• Apriline Hydro requires 3 to 5 repetitions at least 7 days apart;
• Apriline Normal and Apriline Forte involve the organization of only one session; a repeat is needed only after 6 - 12 months.

Recovery usually does not cause any problems. It is important to follow the doctor’s recommendations so that rehabilitation is as successful as possible.

The basic rules are:

• It is forbidden to touch the affected area for two days, much less use cosmetics;
• you need to use anti-inflammatory creams and disinfectants;
• It is prohibited to visit the sauna, even take hot baths, or visit gyms and solariums for the next 2 weeks.

How does the procedure work?

Before starting a course of mesotherapy, the patient is examined by a dermatocosmetologist or trichologist. He determines the area of ​​treatment, eliminates possible contraindications, and draws up an individual injection regimen. The patient is advised to temporarily stop taking medications that reduce blood clotting.

The Apriline mesotherapy session takes place in several stages:

• The skin of the problem area is cleansed of cosmetics and impurities and treated with an antiseptic;
• A cream with a local anesthetic is applied to reduce the pain of the injections;
• The cosmetologist introduces the mesococktail using a syringe with a very thin needle or a mesoinjector. The distance between injections is 1 cm;
• Apriline Hair Line is injected over the entire scalp or only in the area of ​​alopecia;
• At the end of the procedure, the skin is re-treated with an antiseptic;
• A cream with soothing and regenerating properties is applied to the treated area (excluding the scalp).

The duration of the session depends on the area of ​​treatment and the severity of the problem. The procedure can last from 15 minutes to 1.5 hours.

Reviews from patients and cosmetologists

Patient reviews of Apriline can be considered indicative. Most of them are positive, since the result is not long in coming and pleases its owners for a long time. The price-quality ratio of the procedure is quite acceptable. This is also an important characteristic due to which this drug is preferred. Experts and their clients note low risks of side effects, safety for health in general, as well as for the skin.

Plastic surgeons use Apriline to eliminate age-related changes in the skin, thereby stimulating regeneration processes. Doctors also note many excellent results and a low likelihood of serious complications requiring special treatment.

Possible side effects

Immediately after the injections, slight swelling and bruising may appear at the injection sites. With proper care, they disappear on their own in 1-2 days. Possible complications requiring medical attention:

• Inflammatory reactions;
• Changes in pigmentation at injection sites;
• Fibrous skin thickening;
• Vascular embolism;
• The appearance of scars;
• Necrosis of the skin and subcutaneous tissue.

Undesirable reactions may be associated with the characteristics of the body or a violation of the procedure technique.