Biorevitalization with Profhilo - Swiss rejuvenation technology

The new injection drug Profhilo / PROFHILO from the largest Swiss pharmaceutical company IBSA is a hybrid complex of high molecular weight and low molecular weight hyaluronic acid, aimed at remodeling the skin of the face, neck, décolleté, and hands.

The international pharmaceutical company IBSA is one of the leading producers of hyaluronic acid and drugs based on it, exercising full control of the production process from raw materials to the final product. The IBSA company was founded in 1945, and currently it consists of 25 offices and industrial plants in various countries around the world, including Italy, where Profhilo is produced. Constant investment in scientific research and a state-of-the-art production facility have allowed us to create a new product with unique characteristics.

In Italy, sales of the drug began in February 2015, and it entered the world market in January 2021. Currently, Profhilo / PROFHILO is represented in more than 43 countries around the world. In our country, the drug Profhilo / PROFHILO was registered in April 2021, after which it became available to our patients. Currently, its sales are steadily gaining momentum, as it has a number of advantages over other biorevitalization drugs.

Review of biorevitalizant

Biorevitalizant Profile is an innovative product on the market and has unique properties than conventional filler.

During production, the patented NAHYCO heat treatment technology is used, the output is a product with a maximum content of hyaluronic acid.

Thanks to this technique, the composition contains no foreign toxic impurities and stabilizing agents, so-called “chemical cross-links”, which, in turn, eliminates the occurrence of adverse reactions and allergies.

Compound

The Profhilo product contains 2 types of hyaluronic acid with different molecular weights - low and high.

Buyanov Sergey Yurievich (Expert Doctor):

Low molecular weight hyaluronates provide signaling activity to CD44 receptors, which leads to an increase in the production of intrinsic hyaluronic acid.

High molecular weight hyaluronic acid makes up the dermal matrix, which creates a reinforcing effect.

This combination allows for a comprehensive effect on age-related changes, resulting in a “hydrolifting” effect.

The drug is recommended for patients aged 25 to 75 years, and is also actively used during the period of preparation and rehabilitation after plastic surgery. Area of ​​intervention: face, hands, décolleté, forearms.

Manufacturers

The developer is the Swiss company IBSA, which occupies a leading position in the production of products based on hyaluronic acid.

The drug itself is produced in Italy, in one of the divisions of the IBSA Farmaceutici concern.

It should be noted that since the start of sales in 2015, the Profhilo product has won three prestigious awards in the field of aesthetic injection plastic surgery:

• "Anti-Aging Beauty Trophy 2015-2016" - as the best product;
• “Aesthetic Awards” – as innovation of the year.
• "AMEC and Aesthetics Awards 2017" in the category "best injectable product of the year."

Advantages

The use of Profhilo is practiced to correct sagging and signs of aging in the face, neck, inner surface of the forearms and outer hands.

Buyanov Sergey Yurievich (Expert Doctor):

Due to the increased ability to spread around the circumference of the injection, the drug is used in “problem” areas where it is impossible to inject, due to the close proximity of nerve bundles and blood vessels. The biogel is administered 3-4 cm from the dangerous point, the drug “spreads” freely to the required distance.

The main difference between this product and other biorevitalizants is the ability to activate the activity of adipocytes (fat cells), which helps eliminate age-related deficiency of subcutaneous fat tissue.

Features of the drug

This is the world's first drug containing stabilized hybrid complexes obtained using NAHYCO heat treatment technology. Profhilo contains only concentrated hyaluronic acid. There are no additives or impurities. The drug is hypoallergenic, because an undesirable reaction is usually provoked by the auxiliary components of fillers.

The uniqueness of the drug lies in the fact that it activates the vital activity of not only fibroblasts and keratinocytes, but also adipocytes (fat cells), maintaining their viability, which leads to the restoration of its own subcutaneous fat, the deficiency of which is determined with age. Profhilo contains 2 types of hyaluronic acid: high and low molecular weight. The ratio of components is 50 to 50. Thanks to this “cocktail”, the drug has a complex effect:

• low molecular weight acid moisturizes the skin and gives a reinforcing effect;
• high molecular weight improves local blood circulation, stimulates the production of your own collagen, and provides lifting.

After a course of therapy:

• subcutaneous fat and fat layer are restored;
• the skin brightens and becomes radiant;
• pigment spots disappear;
• wrinkles, sagging, folds disappear.

Description of the procedure

For safe and effective administration of the drug, the “five bioaesthetic points” method has been specially developed, which involves injections into certain areas (in 5 places) on each side of the face, away from blood vessels and nerves.

The use of this technique minimizes the risk of side effects and ensures a painless procedure. This also contributes to the most uniform distribution of the gel in the tissues.

The injection takes from 10 to 30 minutes. After the session, time is needed for the substance to be completely and evenly distributed in the tissues. This process usually takes 2-3 days.

How it goes

• Before the session, the skin must be treated with an antiseptic.
• The injections are painless, but if the patient wishes or if the pain threshold is high, it is permissible to apply an analgesic cream.
• This is followed by marking of bioactive points, taking into account the individual anatomical characteristics of the patient.
• The drug is administered using a needle or cannulas into the deep layers of the skin.
• The procedure is completed with a light massage - this stimulates the distribution of the substance in the tissues.

Administration techniques

The number of injections may vary depending on the area the correction is aimed at.

• There are 10 bioaesthetic points on the face (5 on both sides), respectively, 10 injections are used in the process. Using the same principle, the drug is injected into the neck area.
• The inner surface of the shoulder is injected at seven points.
• When correcting changes in the outer area of ​​the hand, only 1 injection is given and the gel is injected using a cannula along 5 vectors directed to the finger bones. This technique is called fan cannula.

Course duration

The number of sessions is discussed at the preliminary consultation and is determined by the severity of the problem.

A standard course consists of 2 procedures. Maintain an interval of 30 days.

In case of severe aging of the skin, an additional session is performed after 2 months.

Features of the new drug and its advantages over traditional analogues

Due to their high fluidity, the components, unlike traditional fillers, pass freely through the skin and subcutaneous tissues. Profhilo is successfully used to correct anatomically complex areas - forehead, neck, submandibular area. After injection, the gel is distributed very quickly, providing an easy, natural, dynamic increase in tissue volume, significantly improving the quality of the skin.

• No pain during and after the procedure (only mild discomfort is possible due to the introduction of a foreign substance under the skin, which completely disappears within a few days), post-injection swelling, papules, and hematomas.
• Minimal risk of inflammation.
• Rehabilitation on average ranges from 24 to 48 hours.
• The first visual result becomes noticeable after 24 hours, the maximum effect appears approximately four months after the end of the course.
• High level of patient satisfaction with the results of the procedure.
• The effect lasts up to 10 months.
• There is an almost complete absence of contraindications and age restrictions (depending on the indications, injection courses are given to patients aged 25 to 75 years).
• Pronounced effect guaranteed after a course of therapy
• Restoration of the fat layer and subcutaneous fat.
• Lightening the skin, providing it with a radiant appearance characteristic of youth.
• Elimination of hyperpigmentation (including age-related changes).
• Correction of wrinkles, folds, sagging skin, the formation of so-called “jowls” and other visual defects (most important for the middle zone of the face, mandibular region).

The gel introduced under the skin forms a single whole with the tissues, moving with them naturally even in anatomically mobile areas.

Healing period

In the world of contouring, 10 injections are considered a relatively minor intervention, so the procedure does not require a recovery period.
Traces of injections disappear after 30 minutes. The first results appear after 2-3 days, during which time the drug is evenly distributed in the tissues.

The maximum effect of stimulating the work of one’s own cells appears within 4 months.

The duration of action is about 8-10 months, after which the course can be repeated.

Possible side effects

The drug is characterized by a high degree of biocompatibility, and therefore there is no risk of serious adverse reactions.

Sometimes (as an exception): mild hematomas, redness and discoloration of the skin at the injection sites may occur. In very rare cases, patients experience pain and itching.

Before launching on sale, this product was tested, according to the results of which the appearance of bruises at injection sites was observed in 12% of patients. The hematomas disappeared within 3 days.

Results of the procedure

Just a day will pass, and you will notice that the skin tightens and becomes smoother and more youthful, the volume of the tissues of the face, neck, and arms is restored - the areas into which Profhilo was injected. Pain, discomfort, recovery period? This is not about Profhilo. If you repeat the procedure in a month, you will improve and fix the effect. Afterwards, a maintenance procedure once every few months will be sufficient.

Yes, it seems like science fiction, but it’s true - just two procedures with an interval of a month are enough. The drug Profhilo has already received several awards in Europe and the USA as an innovative drug in aesthetic cosmetology.

Existing contraindications

Contraindications to biorevitalization are standard.
They are followed by qualified cosmetologists. The procedure is not carried out:

• at elevated temperatures;
• during pregnancy or lactation;
• with individual intolerance to hyaluronic acid;
• in the presence of cancer or infectious diseases;
• in case of blood disease;
• oncological processes, regardless of location;
• if there are fungal or viral skin diseases;
• scars and scars in the injection area.

Mechanism of action of the drug Profhilo / PROFHILO

The mechanism of action of the drug Profhilo / PROFHILO is a multi-level dynamic remodeling of the intercellular matrix of the skin, creating a supporting frame and activating the vital activity of fibroblasts, keratinocytes and adipocytes. The drug represents a new and interesting approach to skin restoration and correction of its atrophy. Can be used on any area of ​​the face and body. Good results have been obtained in the correction of atrophic scar changes, including after acne.

Any injection procedure is preceded by a consultation with a cosmetologist, during which an anamnesis is collected, including a cosmetic one, contraindications are identified, and a course of procedures is selected to correct age-related changes in the skin of the face and body. If necessary, a course of Profhilo / PROFHILO procedures can be perfectly combined with contouring preparations containing hyaluronic acid. This combination is especially effective for achieving aesthetic results in the shortest possible time. The course of Profhilo / PROFHILO procedures has excellent potential for the joint use of hardware methods for correcting age-related skin changes, including Pearl laser peeling on the latest generation Cutera device.

Available in syringes of 2 ml.

Precautionary measures

To reduce the risk of hematomas and inflammation at injection sites, you should follow several tips.
Recommendations before and after the procedure:

• Avoid drinking alcohol the day before the procedure;
• avoid taking aspirin or other anti-inflammatory drugs several days before the session;
• do not use decorative cosmetics for three days after the intervention;
• do not touch injection sites on the day of the procedure;
• hide the injected areas from wind and frost for a week;
• Avoid visiting the gym, saunas, public swimming pools and ponds for three days after the session.

And most importantly, Profhilo injections should only be carried out by a qualified and experienced specialist with knowledge of the anatomy of the injection sites and the technique of invasive interventions.

Preparation

Before carrying out the manipulation, the patient must follow some recommendations to increase efficiency and reduce the likelihood of developing negative reactions. In this case, measures are carried out not only for the skin, but also for the entire body, since its reaction is important for a good result.

Manipulation is more often performed for women of different ages, but men can also undergo it if necessary. The principles of preparation for them are no different, but the day before injections you should not use after-shave lotions that contain alcohol.

Violation of the preparation rules will certainly lead to complications after the manipulation.

Photos before and after

Recovery after Profhilo injections

Skin care after Profhilo injections is simple, but still requires caution if you want to avoid adverse reactions and get the best results. Thus it follows:

• do not touch the injection site;
• do not rub the treated area;
• avoid makeup;
• do not use peelings or scrubs;
• avoid physical stress;
• avoid gyms, swimming pools;
• avoid high temperatures.

These simple rules will help you endure treatment and get a healthy, radiant look with minimal consequences.

Profhilo injections are one of the safest procedures in modern cosmetic medicine. Many patients find injection procedures very comfortable and safe. However, you need to be aware of minor side effects that may occur as a result of using your skin during the injection process:

• pain;
• redness;
• mild swelling;
• light bruising;
• sensitivity;
• irritation.

If you experience any adverse reaction, severe pain, swelling, bruising, or discoloration, tell your doctor immediately and get medical help. This may be a sign of possible inflammation or infection. Be careful and carefully choose the clinic and cosmetologist who will perform the treatment. Latum Clinic specialists offer high-quality Profhilo procedures, the price of which is affordable for girls who want to maintain their beauty and youth for many years.

Comparison with other products

The profile, thanks to the production technology mentioned above, is a record holder in the injection drug industry for the content of hyaluronic acid (64 mg).

Compared to skin boosters, it does not contain alcohol or other impurities. And also, due to the high viscosity of the gel, the drug is successfully used for correction in anatomically complex areas (forehead, neck and under the jaw) - this is the difference with traditional filler.

In addition, biorevitalizant can be used in combination with other hyaluronic acid-based products for more precise correction of age-related defects.

And one more positive difference is that its price is lower than that of products with a similar effect, for example, Radiesse.

Methods of administration of Profhilo

For the face, specialists use the “5 BET” technique. The drug is injected into five points, and the injection sites are selected individually for each patient (they should be free of large vessels and nerve branches). The main focus is on the cheekbones and lower face.

Injection sites in the neck area are determined after studying the anatomical features of the patient. Due to the excellent fluidity of the substance, only a slight force is required to squeeze it out of the syringe. The gel is injected into the subcutaneous layers; deep injection of the drug into the platysma is prohibited.

The drug is widely used in other problem areas. With its help, you can effectively moisturize, smooth and tighten the skin of the lips, hands, décolleté, and eliminate minor skin defects in various parts of the body.

Opinion of cosmetologists

Practicing cosmetologists speak positively about the effects of Profhilo on their pages on social networks and often, after consultation, recommend it to their patients.

Is Profhilo combined with other procedures?

Immediately after using peelings, cleanings and care procedures, Profhilo injections can be performed during the same visit. And if hardware procedures were carried out, then after 7 days you can also carry out the Profhilo procedure. This helps, among other things, enhance the effect of hardware techniques, as it will give the skin an additional resource for self-rejuvenation.

The bioremodeling drug Profhilo is perfectly combined in one procedure with various meso-cocktails. In particular, the use of this drug is officially recommended in conjunction with drugs from the Skinko series. This combination provides a comprehensive effect on the skin, a brighter and more lasting effect.

Make an appointment with an experienced cosmetologist by calling or order a call back on the website, and we will call you back.