The drug "Mezoxanthin": a new approach to biorevitalization

Meso-Xanthin (Mesoxanthin) F199 is a new generation biorepair for skin protection, restoration, and rejuvenation. Unlike conventional injection biorevitalization or mesotherapy, it activates genes that control the rate of cell renewal.

The word “bioreparant” comes from the English “repair” - “repair, correction, repair,” which well reflects the effect of such drugs.

Mechanism of action of the drug

Signs of skin aging appear due to age-related changes and exposure to sunlight.
Due to the fact that cells do not divide quickly enough, tissues do not have time to renew themselves. This results in wrinkles, loss of firmness, laxity, thinning, spots and folds. Meso-Xanthin F199 acts directly on the cause of aging. The product activates genes on which the recovery process depends. This leads to accelerated skin regeneration and renewal. As a result, its quality begins to improve.

The product restores molecules that were damaged during oxidative processes or were partially destroyed due to exposure to aggressive environmental factors and ultraviolet radiation. The drug has a powerful restorative and antioxidant effect. It not only effectively eliminates the signs of aging, but can also be used as a means to prevent them.

Purchasing a peptide complex

It is not difficult to purchase injectable peptide complexes developed by ABG Lab. The drugs are sold in numerous online stores. The cost of a package with 1 unit (1.5 ml of product) of Meso-Xanthin, supplemented by a description, varies in the range of 4–6 thousand rubles.

The price level for other options for intradermal cocktails from ABG Lab is similar. Confidence in the quality of the purchased products will be gained by contacting official representatives of the manufacturer. Clinics and cosmetologists with extensive experience prefer to cooperate only with trusted suppliers.

Composition of the drug

The manufacturer included in the drug:

1. Hyaluronic acid. Saturates the skin with moisture, delivers nutrients directly to the cells, and starts the process of natural collagen synthesis.
2. Amino acids. Required for the creation of updated fibroblast proteins.
3. Fucoxanthin. It affects the unified structure of DNA and RNA, maintaining a stable state of the chain and protecting it from the effects of destructive factors, stimulating the rate of stem cell division.
4. Antioxidants. Promote tissue regeneration and prevent the destruction of cell membranes.
5. Nucleic acids. They act as a regulator in the process of creating elastin and collagen.
6. Growth factors. Slow down skin aging, normalize intracellular metabolism, stimulate microcirculation processes.

Mesoxanthine

Preparations for bioreparation are one of the most interesting trends in modern cosmetology. This group includes new generation products that activate the processes of cellular tissue regeneration and restore our skin much more effectively than traditional biorevitalizants and meso-cocktails.

Mesoxanthin (Meso-Xanthin F199) is a highly active drug, the main feature of which is its effect on the gene structure of cells and the ability to selectively enhance the activity of necessary genes. It is produced by the American company ABG Lab, known for its other product - Mezovarton, which has already received many high ratings from both patients and specialists.

Unlike its “colleague,” Mesoxanthine is suitable not only for the older age group (over 40 years old), but also for younger patients (over 25). At the same time, both drugs are completely compatible and can be used both separately and as part of a comprehensive rejuvenation program.

↑ Composition and action of Mesoxanthine

As a rule, Meso-Xanthin F199 is used to work with the skin of the face, neck and décolleté. Its active ingredients inhibit the aging process of skin cells for a long time, activate their renewal and improve vital functions.

The appearance of age-related skin defects is associated with a slowdown in the process of its renewal: the rate of division of skin stem cells gradually decreases, and the quantitative and qualitative composition of dermal cells deteriorates. The active substances of Mesoxanthine have a powerful restorative effect not only at the cellular, but also at the gene level, significantly prolonging and enhancing the visual rejuvenating effect. As a result of the course, wrinkles are smoothed out, the elasticity and tone of the skin improves, age spots disappear, the severity of the vascular pattern decreases, and a noticeable lifting effect appears.

↑ Indications for use, instructions

Mesoxanthine is used for:

• correction of age-related changes in the skin (loss of tone, decreased elasticity, appearance of wrinkles, deformation of the oval of the face, dehydration);
• preparing the skin for contact with active sun and eliminating the effects of photoaging;
• eliminating hyperpigmentation;
• preparation and rehabilitation after plastic surgery;
• recovery after medium and deep peels, laser dermabrasion, thermal and chemical damage to the skin.

The duration of the bioreparation course with Meso-Xanthin F199 depends on the patient’s age, usually 4-6 sessions, which are often supplemented with Mesovarton injections. The results obtained last for approximately 1 year, after which the procedures must be repeated.

For patients under 40 years of age, the appropriateness of using Mesoxanthine is determined by a specialist, who also prescribes the number of sessions and their frequency, depending on the manifestations of signs of chrono- and photoaging, the depth of wrinkles and other age-related changes in the skin.

↑ Contraindications, complications, side effects

No specific contraindications to Mesoxanthin have been identified to date. You should refrain from injections only in cases common to this type of procedure:

• individual intolerance to the components of the drug;
• presence of autoimmune diseases;
• the presence of acute inflammatory processes or exacerbation of chronic skin diseases at the site of planned administration;
• pregnancy and breastfeeding.

In addition, the drug practically does not cause complications, incl. formation of granulomas characteristic of contour plastic surgery. Known side effects are redness of the skin and various kinds of tactile sensations (from mild itching to pain) at the injection sites, which is also typical for any injection procedures.

↑ How much does Mesoxanthine cost? Current prices

The drug is supplied in individual disposable syringes with a dosage of 1.5 ml. This amount is enough for 1 procedure (face, neck and décolleté).

Since Mesoxanthin appeared in the arsenal of Russian cosmetologists relatively recently, the general “average market” range of its cost has not yet been formed: for example, the price range in Moscow is from 10,000 to 20,000 rubles per session. You can save money by paying for the entire course at once - in this case, some discount is usually provided.

↑ Review from a cosmetologist:

↑ Patient reviews

“For a long time I couldn’t understand what was new about this drug, because it contains the already familiar hyaluronic acid. I myself took a course of Mesoxanthine two months ago. I am 47 years old, the skin on my face has noticeably moisturized, the “parchment” and dryness has disappeared. A month after the injections, I began to notice that the skin was smoothing out, i.e. The full effect is not visible immediately, but after some time. I’m glad that this drug has undergone clinical trials in our country, which means its effectiveness can be trusted!” (Author of review: Vitolina, St. Petersburg)

“And I would be very careful about new drugs, like Meso-Xanthine. Fortunately, I’m still 18 years old and it’s still too early to use it. But my mother’s friend went for injections twice, and she developed terrible rashes all over her face. The cosmetologist said that this is due to increased sensitivity to hyaluronic acid. It’s good that she refused further injections, otherwise she wanted to pierce her face and décolleté area. In general, the smart thing to do is to first go to a good dermatologist for a consultation and take the necessary tests for allergies, etc. Because not all cosmetologists are such professionals, they just want to get money for procedures and attract more clients with a new drug. Women, be careful, it’s better to go to a good, trusted clinic!” (Author of review: Ksenia, Tyumen)

“I would like to share information from attending a conference organized specifically for cosmetologists, dedicated to the drug Mesoxanthin. I learned a lot about the composition of this drug. Now I won’t tell you everything in detail, it’s very long. I just want to say that I, as a professional cosmetologist, took it to work, and it showed itself most successfully in patients under the age of 35. There the effect is visible almost immediately. Almost everyone notices an unusual “glow” of the skin after injections. There are practically no side effects. One of my clients (she is 38 years old) had red papules for several days, but now everything is fine. It all depends on the state of “neglect” of the skin, and of course on age. She noted that an excellent lifting effect is obtained, skin tone increases significantly. The changes are especially noticeable in the oval of the face after a whole course of injections. The whole course consists of four procedures with an interval of 8-10 days" (Author of review: Ksenia, Moscow)

“Why does everyone say that you only need 4 procedures for a full course of Mesoxanthine? I was prescribed as many as 8 procedures, the interval was at first 7 days, and then increased to two weeks. I was prescribed these injections after biorevitalization. The injection was not from a cosmetologist, but from a dermatologist in the clinic, since the drug was prescribed by the attending physician. Indeed, skin tone has noticeably increased, wrinkles have almost disappeared. But unpleasant skin lumps remained at the injection sites for a long time. Now, three weeks after the last session, everything is fine. I can say from personal experience that such innovative drugs are really needed, they greatly help smooth out the skin. Especially when used in conjunction with other anti-aging procedures!” (Author of review: Alena, Moscow)

Advantages of the drug

Using the product is associated with the following advantages:

• skin renewal is stimulated at the cellular level;
• can be used to prevent age-related changes, so it is acceptable to use the drug on young skin;
• the components of the drug have been well studied, and their effect is easily predicted;
• it is possible to create a favorable environment for fibroblasts to work;
• The product allows you to neutralize free radicals that accumulate under the influence of stress and the sun and lead to premature aging.

Healing period

Performing multiple injections using the biorevitalization technique is always accompanied by redness, swelling, and the formation of papules on the skin. Typical side effects of the procedure are swelling, bruising, and discomfort in the affected areas. Symptoms are present for up to 2–7 days and resolve without additional intervention.

To avoid complications on the day of the procedure, after performing injections, exclude the usual washing and refuse to use cosmetics. Attempts to disguise the consequences of the intervention are strictly prohibited. You can apply makeup only after the injection wounds have completely healed.

During the rehabilitation period after Mesoxanthin injections, the doctor will recommend observing restrictions. It is forbidden:

• is in direct sun, sunbathe in a solarium;
• be exposed to stress by playing sports or physical labor;
• swim in pools and bodies of water open to public use;
• steam, wash in hot water;
• perform skin procedures not approved by a cosmetologist.

The result of Meso-Xanthin injections is noticeable after the end of the rehabilitation period: the skin becomes fresh, healthy in appearance, fine wrinkles disappear, medium and deep folds are reduced. The expected anti-aging effect is noticeable only after completing a course of procedures: the tissues become denser, the skin returns to the turgor characteristic of a young body. The maximum positive result is formed 1–2 months after completion of therapy and lasts up to 12 months.

Indications

It is recommended to undergo biorevitalization with Meso-Xanthin f199 in the following cases:

• early nasolabial folds appeared;
• skin is tight and dry;
• hyperpigmentation is observed;
• unhealthy complexion, dark circles under the eyes;
• the presence of facial wrinkles, the oval of the face has blurred.

Additionally, the products are used during recovery after laser resurfacing, peeling or excessive exposure to the sun.

What effect do injections give?

Meso-Xanthin F199 injections neutralize the causes of skin aging. Thanks to this, a quick, comprehensive rejuvenating and lifting effect is achieved:

• wrinkles are reduced, smoothed out,
• pigment spots fade or disappear completely,
• skin color becomes young, healthy,
• skin elasticity increases, it becomes denser,
• turgor is restored,
• the vascular pattern disappears,
• the skin is tightened,
• oval and facial contours improve,
• enlarged pores become smaller,
• The water and fat balance of the skin is normalized.

Thanks to the rapid formation of young fibroblasts, the concentration of collagen and hyaluronic acid increases, its moisture is restored, and dryness disappears. Metabolic processes return to youthful mode.

How does the procedure work?

Biorevitalization takes about 40 minutes. It is carried out according to the following scheme:

1. Initial consultation. The doctor communicates with the patient, finds out the presence of contraindications and individual characteristics.
2. Treatment of the affected area. The cosmetologist will remove all makeup and perform antiseptic treatment of the skin.
3. Local anesthesia. It is performed using an injection or applying a special cream.
4. Administration of the drug. The doctor will administer the product at several points at once.
5. Leather processing. The cosmetologist will apply an anti-inflammatory and soothing agent.

Contraindications and side effects

To date, no absolute contraindications to the use of the drug have been identified. But you should refuse injections of the biorevitalizant Mesoxanthine in the following cases:

• Individual intolerance to the components included in the composition;
• The presence of inflammatory processes in the area of ​​planned injections;
• Diagnosed autoimmune diseases;
• Pregnancy and lactation period.

In practice, it has been proven that the drug never causes granulomas and scars accompanying plastic surgery. Possible side effects sometimes include redness and mild itching or soreness directly at the site where the needle was inserted. All side effects, even if there are bruises or swelling at the site where the needle was inserted, will disappear within 5-7 days.

The required duration of the bioreparation course with Mesoxanthin depends on the patient’s age, skin condition, level and number of problems to be eliminated. The timing and volume of drug administration are determined by the cosmetologist individually after a personal examination of the patient. This is especially important for people under the age of 40 who have minor skin problems associated with chrono- or photoaging.

The standard Mesoxanthine course consists of only 4-6 sessions. To enhance the desired effect, additional injections of Mesovarton can be performed. The achieved result lasts for about 1 year, after which the course can be repeated.

Mesoxanthine is available in 1.5 ml syringes. This volume is enough to carry out 1 procedure in the selected area. The total price of the course will directly depend on the required volume of the drug.

Administration technique

There are several options for administering drugs for biorevitalization. For Mesoxanthine, as for other formulations containing hyaluronate, several techniques are used, each of which has its own characteristics.

Most often, the intradermal method is used, which does not involve the formation of papules in the treatment areas. The intradermal injection technique is most effective for treating acne and post-acne marks, but other technologies can be used to eliminate age-related changes.

Mesoxanthine injection therapy involves several standard administration techniques:

• Picotage (French picotage). A microinvasive technique that involves the introduction of Mesoxanthine pointwise into the layers of surface tissue, the distance between injections is no more than 1 cm. The French method ensures intensive work of hyaluronic acid in the Grenz zone, activating the synthesis of substances and fibroblasts. The remaining components of the drug penetrate deep into the cellular structures. The use of picotage is recommended for those with young skin for preventive purposes or when the first signs of aging appear.

• Point by point. This technique is carried out in a series of microinjections, the punctures follow strictly one after another, lining up a line along wrinkles or other problem areas. This technique of introducing Mesoxanthine is used in delicate areas - periorbital and perioral. It is less painful.
• Papular. The essence of this biorevitalization technology is intradermal invasions, after which small papules are formed. The needle is inserted to a depth of no more than 1-2 mm. After the administration of Mesoxanthine, papules ranging in size from 2 to 5 mm are formed. The papular technique allows you to prolong the effect of the drug, since diffusion slows down in papules. Recommended for biorevitalization of large areas. The method is the most economical, since the consumption of the product is reduced by 1.5 times. This method of administration is also used for structural regeneration of skin with visible age-related changes.
• Short linear. The technique is intended to create long-term skin hydration, normalize hydrobalance with potentiation of the action of hyaluronate. The cosmetologist determines the treatment area by marking problem areas with short lines. The needle is inserted 2/3, the angle of inclination is 30-45 degrees. The composition is administered in small droplets on the reverse stroke of the needle with a distance between injections of 0.5-1 cm.

The choice of method of administration of the Mesoxanthine composition is determined by a qualified cosmetologist after examination, assessment of the medical or aesthetic problem, as well as collection of a previous cosmetic history.

Indications for injections with this gel

There are almost no complications from the product. It can be used in cosmetology to solve a variety of problems.

Mesoxanthine injections are needed for:

• getting rid of scars (can be combined with other methods);
• skin restoration after peelings and other procedures;
• preparation for plastic surgery; the drug can also be prescribed during rehabilitation after it;
• combating the signs of photoaging and preventing it. This is also preparation for active insolation;
• correction of age-related changes in the skin (loss of elasticity and firmness of the skin, changes in the oval of the face, dehydration of the skin).

Customer Reviews

“I’m only thirty years old, but I already have a lot of skin problems. In similar cases, my aunt used Mezovarton with peptides, and the condition of her skin improved, but the cosmetologist did not inject me with this drug, because this gel is suitable for women over forty years old.

In another salon where my friend works, I was offered to try a product similar to Mezovarton. It also contains peptides, but young people also use the drug.

I can tell you there is an effect. The appearance of the skin has improved significantly, the skin has stopped drying out, the oval of the face has tightened, the skin turgor has increased, and wrinkles have smoothed out. But most of all, I was happy that the pigment spots that appeared after pregnancy became less noticeable. I completed six sessions and did not regret my decision. My friends started complimenting me.”

(Svetlana, 30 years old)

"Good day! A week ago I underwent a biorevitalization procedure. The price of the injections was 9,000 rubles. Yes, the cost is really not cheap.

The injections take about forty minutes. The gel is injected under the skin using a thin needle. The drug is injected around the entire perimeter, excluding the nose area. Pimples appear on the skin after the session, in addition, the injection area turns red.

The redness should go away after about two to three hours. The pimples begin to disappear approximately on the second day. Every day they decrease. I can say from personal experience: I have sensitive skin, and already on the fourth day almost everything went away.

The result is not immediately visible. I can’t analyze it right away, but I feel that the skin has tightened. Now she looks healthy. On the first day after injections, you can wipe the area with Miramistin. You cannot use any decorative cosmetics. A day later, the cosmetologist allowed me to use skincare creams and other products. But you can’t go to the sauna, steam bath, or use a warming mask.”

(Sofia, 35 years old)

“Biorevitalization and mesotherapy are now being discussed by many. Some people like these procedures, others don’t. I can tell you about my impressions.

In winter, I had a course of biorevitalization (three sessions with a break of two weeks) using the drug Mesoxanthin. The gel is included in the group of bioremediation agents, but this does not change the essence. Because in any case, it is based on the intradermal injection of a product made with hyaluronic acid in the composition.

Due to the fact that I relatively recently finished breastfeeding my child, and before that, of course, I was pregnant, I did not go to a cosmetologist for at least two years. And I decided to visit a specialist only when my dry, sensitive skin turned red and began to peel off, and my expression wrinkles worsened.

The product “Mezoxanthin” was selected for me by a cosmetologist. But I can write a few words about the gel. Mesoxanthin is used not only to moisturize the skin, but also to combat the signs of aging, which is important for me. What result did I expect: moisturizing the skin, increasing skin tone, improving its general condition. The description of the gel can be found on the Internet, so I see no point in repeating it here.

In addition, I liked the composition of this product. Recently I began to carefully read the ingredients of cosmetic products. This helps me make the right choices. If the composition contains unstabilized hyaluronic acid, then the hydration will be wonderful. The instability of hyaluronic acid indicates the absence of stable bonds between the particles of the drug. After introducing the gel, the particles will disintegrate. This ensures uniform hydration of the skin.

Moreover, the composition contains a carotene preparation - fucoxanthin (Fucoxanthin F-199). I found some interesting information on the Internet. It turns out that carotenoids are pigments that are synthesized by plants, fungi and bacteria. They are not soluble in water and are similar to retinol. Carotenoids are considered a factor that protects the body from photoaging and tumor formation. Fucoxanthin, obtained from seaweed, also acts at the intracellular level.

The Meso-Xanthin f199 gel contains nucleic acids, peptides, and a complex of vitamins. Agree that the composition is really good. I made this conclusion not based on advertising, but thanks to the analysis of each component separately.

I answered the cosmetologist that I agree to use this gel. But even without studying the composition of the product, I trust my specialist.

Before the injections, as usual, I was given a cream with an anesthetic component. As soon as it took effect, they started giving me injections. I went through the procedure three times, and each time the pain was felt differently. But in general I can say that I could tolerate the pain.

On the first and second days there were papules on the face. On the third day they turned into red dots that are not visible under a layer of foundation.

On the fourth day there were no traces left. On the fourteenth day it was necessary to go for injections again.

At the moment I see the effect. My friends noted that I had a refreshed and rejuvenated appearance.

Frankly speaking, I am happy that I received these injections. I recommend them to all ladies from thirty to forty years old who have low skin tone and dry and sagging skin.

The secret to the success of not only biorevitalization, but also other cosmetic manipulations lies in their correct selection. Never fall for advertising or do something just because someone else has done it.

Of course, it is very important to consult a good specialist. However, if you don’t have an experienced cosmetologist among your friends, then:

• analyze your skin condition. Think about what she is missing. My skin needed hydration, so I preferred a gel with unstable hyaluronic acid. If your skin is sufficiently moisturized, then think about mesotherapy, vitamin cocktails or, for example, improving your complexion, if this is the problem;
• Find information about medications that can relieve you of cosmetic imperfections. Read the composition of the products: does it correspond to the effect declared by the manufacturer. Are there any additional components that can aggravate skin problems, or highly allergenic components;
• do not forget to control the drugs that the specialist administers to you. Check the tightness of the packaging and the expiration date of the gel.

Always be beautiful and happy, because we all deserve it!”

(Zhanna, 34 years old)