Solcoseryl (gel), 1 pc., 20 g, gel for external use

Composition and release form

in ampoules of 2 ml; there are 25 ampoules in a box; or in ampoules of 5 and 10 ml; There are 5 ampoules in a box.

in tubes of 20 g; 1 tube in a box.

in tubes of 20 g; 1 tube in a box.

pharmachologic effect

Pharmacological action - antihypoxic, cytoprotective, regenerating, membrane stabilizing, angioprotective, wound healing.

The drug Solcoseryl is a deproteinized hemodialysate containing a wide range of low-molecular components of cell mass and blood serum of dairy calves with a molecular weight of 5000 D, the properties of which are currently only partially studied by chemical and pharmacological methods.

In in vitro tests, as well as during preclinical and clinical studies, it was found that Solcoseryl:

— increases reparative and regenerative processes;

— promotes activation of aerobic metabolic processes and oxidative phosphorylation;

— increases oxygen consumption in vitro and stimulates glucose transport into cells under hypoxic conditions and into metabolically depleted cells;

— increases collagen synthesis (in vitro);

— stimulates cell proliferation and migration (in vitro).

Solcoseryl gel does not contain fats as auxiliary components, making it easy to wash off. Promotes the formation of granulation tissue and the elimination of exudate.

From the moment fresh granulations appear and the wound dries, it is recommended to use Solcoseryl ointment, which contains fats as auxiliary components and forms a protective film on the wound surface.

Active substance Solcoseryl

Solcoseryl is available in the form of ointment, gel, tablets, cream, injections. In order to assess the extent of the drug’s effect on the skin, let’s find out what is included in its composition. The active substance is an extract from the blood of calves, freed from protein. This is blood plasma without fibrinogen, otherwise - deproteinized hemodialysate.

The drug has a high degree of bioavailability. Due to its high degree of purity and low molecular weight, it easily penetrates the cell wall.

The impact of this multicomponent substance is difficult to analyze in detail. The reason is that the components of Solcoseryl are normal physiological inclusions of any organism.

Little knowledge of Solcoseryl is the reason that it is approved for use in a limited number of countries. Russia and the CIS countries are the main sales market. Doctors in these countries see its effectiveness and do not need to confirm it through additional research.

Canada, USA, Japan, Australia and Western European countries have not approved the drug as a medicine. Moreover, there were scandalous cases when athletes who used the drug to speed up the healing of injuries were disqualified.

Indications for the drug Solcoseryl

Solcoseryl solution for injection.

Occlusive diseases of peripheral arteries in stages III–IV according to Fontaine in patients with contraindications/intolerance to other medications;

chronic venous insufficiency, accompanied by trophic disorders (Ulcera cruris), in cases of their persistent course;

disorders of cerebral metabolism and blood circulation (ischemic and hemorrhagic stroke, traumatic brain injury).

Solcoseryl gel, ointment.

Minor damage (abrasions, scratches, cuts).

1st and 2nd degree burns (sunburn, thermal burns).

Frostbite.

Difficult-to-heal wounds (including trophic ulcers and bedsores).

Deproteinized dialysate from calf blood - indications for use

The list of indications for the use of Solcoseryl ointment is determined by the presence in the drug of a large number of various growth factors and active components that stimulate the process of regeneration of damaged tissues. The drug is indicated for therapy in the following cases:

• abrasions, scratches and cuts to the skin,
• sun or thermal burn of the skin (1-2 degrees),
• frostbite,
• the presence of trophic ulcers and bedsores,
• dry, crusty wounds on the skin and red border of the lips.

Reviews from patients and doctors about Solcoseryl ointment are quite positive, and they say that the drug accelerates wound healing by about 25-30%. It should be noted that some patients try to use Solcoseryl as an ointment for wrinkles (for cosmetic purposes). There is a certain logic in this, because... the active substances of the drug actually promote the proliferation of fibroblasts and enhance their activity. We will discuss this aspect of application in more detail in the “Reviews” section.

Important: once again we draw your attention to the fact that the instructions for use for Solcoseryl ointment contain clear instructions that the drug can be used to heal wounds on the skin - only if the surface of the wound is dry and there is no wet discharge (exudate, ichor). To accelerate the healing of fresh wounds that are not yet covered with granulations/crusts, as well as those with wet discharge, Solcoseryl is used in gel form.

We also draw your attention to the fact that despite the fact that all forms of Solcoseryl (ointment, gel and dental paste) - although they have a similar list of active ingredients, the ointment form of this drug should not be used on the oral mucosa. This is due to the fact that the fatty substance of the ointment does not adhere well to the moist mucous membrane and is instantly swallowed. To speed up the healing of the oral mucosa, it is better to use Solcoseryl dental paste.

Contraindications

Solcoseryl solution for injection.

Established hypersensitivity to calf blood dialysates;

since Solcoseryl injection contains derivatives of parahydroxybenzoic acid (E216 and E218), used as preservatives, as well as trace amounts of free benzoic acid (E210), the drug should not be used if there is an allergic reaction to the listed components;

There are no data on the safety of Solcoseryl injection in children, so the drug should not be prescribed to children under 18 years of age;

Solcoseryl injections should not be mixed when administered with other drugs, with the exception of isotonic sodium chloride solution and 5% glucose solution.

Solcoseryl gel, ointment.

Hypersensitivity to one of the components of the drug.

Use with caution if you are predisposed to allergic reactions.

Advantages and disadvantages

The advantages of the drug include its availability and high efficiency. The cost of Solcoseryl in a pharmacy is 300 rubles. For healing wounds from removed ulcers, as well as for getting rid of their consequences, this remedy is considered one of the best. Acting quickly and reliably, the medicine provides different methods of application, depending on the phase of the disease.

Disadvantages when using it:

• the drug may cause an allergic reaction,
• requires targeted application, can damage those pimples and blackheads where the inflammatory process is still ongoing,
• with abundant and frequent use, the ointment can clog skin pores.

Solcoseryl is an excellent natural remedy that helps get rid of spots after ulcers and rashes. This drug is easy to buy at the pharmacy, but it must be used with caution, strictly following the instructions for use. It is important to remember that Solcoseryl does not treat acne itself, but only eliminates its consequences, making the skin smooth and clean. To relieve acute inflammatory processes, it is necessary to select other medications, consulting a dermatologist.

Side effects

Solcoseryl solution for injection.

In rare cases, allergic reactions may develop (urticaria, hyperemia and swelling at the injection site, increased body temperature). In this case, it is necessary to stop using the drug and prescribe symptomatic treatment.

Solcoseryl gel, ointment.

In rare cases, allergic reactions in the form of urticaria and marginal dermatitis may develop at the site of application of Solcoseryl. In this case, you must stop using the drug and consult a doctor.

A short-term burning sensation may be observed at the site of application of Solcoseryl gel. If the burning sensation does not go away for a long time, the use of Solcoseryl gel should be abandoned.

Effective in treating scars and scars

The result of using the drug Solcoseryl depends on the correct application, the condition of the wound, and the stage of healing:

• Old scars that are blackened or dark in color are difficult to get rid of with ointment or gel. Liniment affects the formation of scar tissue, but the effect is weak in the fight against old scars. To achieve a noticeable positive change in the scar area, it will take at least 1 month of regular use of cream liniment.

Treatment of scars with gel and ointment is effective during the healing period of wounds and ulcers. The product helps prevent the formation of atrophic, keloid scars, and stretch marks on the skin. Experts recommend using Solcoseryl for rapid regeneration of sutures after surgery and achieving maximum cosmetic effect.

• For post-acne and chickenpox, the drug is used to prevent the formation of scars, scars, dimples, spots, and other defects on the face and body. An important condition for using the gel and cream is its application during the period of attenuation of inflammation at the site of acne, papules from chickenpox. The drug does not have an anti-inflammatory effect. But its ability to activate metabolism, saturate the skin and tissues with oxygen and amino acids, can enhance the inflammatory process and increase hyperemia in problem areas.

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Solcoseryl can be used after eliminating inflammation on the skin due to acne. It will help heal damage, smooth out uneven skin, and get rid of acne spots. Likewise with smallpox marks. Solcoseryl for scars after chickenpox can be applied only during the period of extinction of the disease, when there are no new rashes, and in existing wounds the inflammatory process has subsided.

Interaction

Solcoseryl injections should not be mixed when administered with other medications, especially with phytoextracts.

The pharmaceutical incompatibility of Solcoseryl in the form of an injection solution with parenteral forms has been established:

Ginkgo biloba extract,

naftidrofuryl,

bencyclane fumarate.

As solutions for diluting Solcoseryl injection, only isotonic sodium chloride solution and 5% glucose solution should be used.

The interaction of Solcoseryl with other topical medications has not been established.

Reviews

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Reviews from cosmetologists and patients are quite contradictory.

Most note the effectiveness of Solcoseryl in the fight against spots and marks after acne, and a good effect on aging skin.

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Directions for use and doses

Solcoseryl injection solution: intravenous or intramuscular.

In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine - 20 ml intravenously daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.

In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris) - 10 ml intravenously 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.

In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.

In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms, the main course is 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.

Traumatic brain injury (severe brain contusion) - 1000 mg intravenously, daily for 5 days.

If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.

When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.

Solcoseryl gel, ointment: topically.

Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.

Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.

Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.

Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.

Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.

For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.

Good gels

Ointments for the treatment of scars are recommended to be applied morning and evening, and if possible, once at night if the ointment has a fatty base. The best option for using the ointment would be a night ointment bandage, which will allow any product to be deeply absorbed and have an effect for several hours.

Creams have a light consistency, and most often take the form of an emulsion, which penetrates into the depths of the skin not as deeply as an ointment, but deeper than gel-based preparations. The cream can be applied several times a day; after a few minutes of massage, it does not stain clothes or leave greasy marks on them, unlike ointment, which is therefore advisable to apply at night or under bandages.

The most common remedy for combating scar-like damage is gels. This format is very convenient to use. Gel preparations accelerate the healing of scars and are an excellent method of preventing their formation.

Gel "Silicone". An effective drug for scars resulting from mechanical injuries, as well as stabs. Replenishes collagen in the skin, stimulating rapid regulation. Recommended for preventing the appearance of skin defects.

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"Kontraktubeks". The product is part of the newest group. Made in Germany. This country is famous for the high-quality production of not only technology, but also many medicines, including cosmetics. Having a high cost, the Kontraktubeks brand of gel is effective in the fight against scars resulting from deep abrasions, soft tissue ruptures, surgical interventions and burns. A high therapeutic effect was also noticed in the treatment of scars from skin diseases, acne and scars from laser surgical interventions.

“There are no scars.” This drug is very cheap, costs about 50 rubles. Improves the appearance of the scar, helps accelerate tissue recovery. Consists of allantoin, hyaluronic acid, heparin, rutin, vitamins and extracts that improve blood flow.

"Derma-Cat." Treats scars after surgery, burns, stretch marks, keloid scars, scars after chickenpox, acne, acne, as well as the consequences of laser surgery. The uniqueness of the gel lies in its ability to hide and smooth out painful changes on the skin from thermal, chemical and mechanical damage, which makes it universal.

"Scagel". The drug is used on both old and new scars. The effect is achieved due to the content of components that act in stages throughout the development of the scar. Thanks to the gel in the wound, stable production of collagen of the first and third types is ensured. The active ingredient is emblica seed extract.

Gel "Hiruskar" for removing scars and stretch marks. Costs about 1,000 rubles. The product is produced using effective technology and is the latest development of the Medinova brand (Switzerland). The company has been creating aesthetic cosmetics for over forty years. Its products for scars and stretch marks can cope with both fresh scars and already healed scars. Frequent treatment makes defects invisible and smoothed out. The same effect has a beneficial effect on stretch marks (stretched skin tissues).

"SCAR" by Mela clear. The drug contains vitamin E and is aimed at eliminating acne scars. The gel actively penetrates into the upper epidermis and does not leave its traces on the surface in the form of oily smudges. Perfect for applying to any part of the body. In addition, many women prefer the gel for mosquito and other midge bites. SCAR also makes imperfections in the form of rashes, scars and scratch scars invisible.

"Hiruscar." The gel has a highly antibacterial formula. Treats scars of various etiologies, except for fistulous and colloid defects. Effective in several functions: lightening, removing redness, reducing scar depth, blocking the appearance of new rashes and scar-like blemishes.

"Fermenkol" is a product for professional care of the upper epidermis on various parts of the body. It is sold in the form of one ampoule with the active substance and a gel-like composition in another tube. Both parts are mixed into one elixir. Heals fresh formations, makes the scar inconspicuous.

"Stratamed". It is used for open wounds and places with damaged integrity of the integument. Treats imperfections after surgical operations, burn consequences, restores skin after animal bites, scratches, acne. Ideal for treating scars caused by laser beams, tattooing, chemical exposure, and dermabrasion.

The mechanism of operation of all gels is based on the formation of a gas-tight and waterproof silicone gel protective layer that can moisturize the scar and ensure safety when the skin comes into contact with chemical and bacterial irritants.

special instructions

Solcoseryl (gel, ointment) should not be applied to a contaminated wound, since it does not contain antimicrobial components.

The use of Solcoseryl, like all other medications, is undesirable during pregnancy and breastfeeding and is possible only when absolutely necessary and under the supervision of a doctor.

If you experience pain, redness of the skin near the site where Solcoseryl was applied, secretion from the wound, or increased body temperature, you should immediately consult a doctor.

If, when using Solcoseryl, healing of the affected area is not observed within 2-3 weeks, you should consult a doctor.

Clearvin – cream

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Clearvin is a popular dietary supplement based on the knowledge of Indian medicine - Ayurveda. It contains various antioxidants and extracts of many plant components. Experts recommend using Clearvin not so much for the treatment of rough scars and cicatrices, as for the prevention of their occurrence, if there are fresh wounds or scratches on the skin.

Clearvin can be used in both adults and children. The creamy consistency allows it to penetrate deep enough into the skin, improves the absorption of oxygen into tissues, and the amount of melanin synthesized in the skin decreases with regular use. This allows, even if the scar has already formed, to make it less noticeable and non-pigmented. Clearvin is used to treat stretch marks, including in pregnant women.

They are also popular for the appearance of age spots on the skin of the face, as well as for the treatment of acne (acne), in combination with other products. Clearvin is used twice a day, or more often. The product is produced by the domestic company Realcosmetics, and the price is very affordable: one tube weighing 25 g can be purchased in a retail pharmacy chain even for 70 rubles.

Advantages and disadvantages

The advantage of Clearvin, without a doubt, will be its rich natural composition and low cost. Clearvin can be used in children, and this is also a big plus. However, before applying the cream, you must first prepare the skin by thoroughly washing the area of ​​application with regular soap, or first remove makeup if the cream is applied to the skin of the face.

Clearvin, in the absence of individual intolerance, may be indicated for application to the skin of pregnant women to treat stretch marks, but before this it is necessary to first test the tolerability of the cream by applying it to the delicate skin of the elbow. It is contraindicated if a person has an allergic reaction to turmeric, aloe, and many other ingredients. Since there are so many of them, the only way to check tolerance is to test the cream on the skin.